MEAF6 and L3MBTL2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MEAF6	L3MBTL2
Description		MYST/Esa1 associated factor 6	L3MBTL histone methyl-lysine binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Nucleolus NuA4 Histone Acetyltransferase Complex MOZ/MORF Histone Acetyltransferase Complex NuA3a Histone Acetyltransferase Complex NuA3b Histone Acetyltransferase Complex	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Histone Acetyltransferase Activity (H3-K23 Specific)	Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding
	Biological Process	Histone H2A Acetylation Histone H3-K23 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Histone H3-K14 Acetylation Regulation Of Signal Transduction By P53 Class Mediator	Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways		HATs acetylate histones HATs acetylate histones Regulation of TP53 Activity through Acetylation	SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045)	Adventurousness ( 30643258) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Schizophrenia ( 25056061 29483656)
Interacting Genes		7 interacting genes: CCDC85B FXR2 L3MBTL2 LDOC1 MRGBP PLEKHF2 TRIM54	17 interacting genes: BEND7 CYB5R3 H3C1 H4C1 LNX2 MEAF6 MPP3 PAICS PHF10 PIAS1 STAC3 STAM2 TBC1D9B TLE5 TRIM42 ZFP64 ZFY
Entrez ID		64769	83746
HPRD ID		13347	13954
Ensembl ID		ENSG00000163875	ENSG00000100395
Uniprot IDs		Q9HAF1	A0A0S2Z5X6 Q969R5
PDB IDs			2W0T 3CEY 3F70
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?