L3MBTL2 and PIAS1

  • Number of citations of the paper that reports this interaction (PubMedID 24369422)
  • 11
  • Data Source:
  • BioGRID (enzymatic study)

L3MBTL2

PIAS1

Description L3MBTL histone methyl-lysine binding protein 2 protein inhibitor of activated STAT 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Crohn's disease ( 26192919)
  • Depression ( 29700475)
  • General risk tolerance (MTAG) ( 30643258)
  • Inflammatory bowel disease ( 26192919)
  • Major depressive disorder ( 27479909)
  • Neuroticism ( 29255261 27918536)
  • Schizophrenia ( 25056061 29483656)
Interacting Genes 17 interacting genes: BEND7 CYB5R3 H3C1 H4C1 LNX2 MEAF6 MPP3 PAICS PHF10 PIAS1 STAC3 STAM2 TBC1D9B TLE5 TRIM42 ZFP64 ZFY 107 interacting genes: AKT1 AR ATXN1 AXIN1 BARD1 BRCA1 CASP8 CBS CDK4 CEBPA CEBPE CHUK CNOT7 CREB1 CREBBP CSNK2A1 CSRP2 DCLRE1A DDX21 DDX5 DNM1 DNMT3A ELK3 EP300 ESR1 ESR2 FANCI FHL3 FLI1 GATA4 GLUL GRM8 GSK3B GTF2IRD1 HECTD2 HIC1 HTT IKZF5 JUN KLF3 L3MBTL2 LSM3 MAML1 MBD1 MDC1 MDM2 MITF MSX1 MX1 MYB NCOR1 NFATC1 NIN NR2F2 NR3C2 NR5A1 PAXIP1 PGR PIAS2 PIAS4 PLAG1 PML PPP1CA PPP1CC PRDM1 PRPF40A PSME3 PTK2 PTPN1 QKI RAD54L2 RBBP6 RELA SATB1 SATB2 SERBP1 SGTA SKIL SMAD1 SMAD4 SMAD7 SNAI2 SNIP1 SP3 SPOP SREBF2 STAT1 SUFU SUMO1 SUMO1P1 SUMO2 SUMO3 TBP TERF2 TEX11 TP53 TP73 TRIM27 TRIM5 TRIM55 TRIM63 TSG101 UBE2I UBE2L3 YWHAZ ZNF451 ZNF76
Entrez ID 83746 8554
HPRD ID 13954 16029
Ensembl ID ENSG00000100395 ENSG00000033800
Uniprot IDs A0A0S2Z5X6 Q969R5 O75925 Q1XBU8
PDB IDs 2W0T 3CEY 3F70 1V66
Enriched GO Terms of Interacting Partners?
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