L3MBTL2 and ZFY

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		L3MBTL2	ZFY
Description		L3MBTL histone methyl-lysine binding protein 2	zinc finger protein Y-linked
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm Nucleolus
	Molecular Function	Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition	Regulation Of Transcription By RNA Polymerase II
Pathways		SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs			Beta-Cyclohexyl-Alanine PCL-016
Diseases
GWAS		Adventurousness ( 30643258) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Schizophrenia ( 25056061 29483656)
Interacting Genes		17 interacting genes: BEND7 CYB5R3 H3C1 H4C1 LNX2 MEAF6 MPP3 PAICS PHF10 PIAS1 STAC3 STAM2 TBC1D9B TLE5 TRIM42 ZFP64 ZFY	2 interacting genes: L3MBTL2 ZBTB9
Entrez ID		83746	7544
HPRD ID		13954	02466
Ensembl ID		ENSG00000100395	ENSG00000067646
Uniprot IDs		A0A0S2Z5X6 Q969R5	P08048
PDB IDs		2W0T 3CEY 3F70	1KLR 1KLS 1XRZ 5ZNF 7ZNF
Enriched GO Terms of Interacting Partners?
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