L3MBTL2 and STAC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		L3MBTL2	STAC3
Description		L3MBTL histone methyl-lysine binding protein 2	SH3 and cysteine rich domain 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm Cytosol Voltage-gated Calcium Channel Complex T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Synapse
	Molecular Function	Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition	Skeletal Muscle Contraction Neuromuscular Synaptic Transmission Intracellular Signal Transduction Skeletal Muscle Fiber Development Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Adventurousness ( 30643258) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Schizophrenia ( 25056061 29483656)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 25056061 29483656)
Interacting Genes		17 interacting genes: BEND7 CYB5R3 H3C1 H4C1 LNX2 MEAF6 MPP3 PAICS PHF10 PIAS1 STAC3 STAM2 TBC1D9B TLE5 TRIM42 ZFP64 ZFY	19 interacting genes: BAZ2B C1orf35 CSNK2A1 DIP2A EAF1 EAF2 ENKD1 FAM124A FAM133A FAM90A1 JMJD6 L3MBTL2 MAB21L3 NKAPD1 NSD3 PPARA SREK1IP1 ZCCHC10 ZGPAT
Entrez ID		83746	246329
HPRD ID		13954	11606
Ensembl ID		ENSG00000100395	ENSG00000185482
Uniprot IDs		A0A0S2Z5X6 Q969R5	A0A024RB38 Q96MF2
PDB IDs		2W0T 3CEY 3F70	2DB6 6B29
Enriched GO Terms of Interacting Partners?
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