MEAF6 and PLEKHF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		MEAF6	PLEKHF2
Description		MYST/Esa1 associated factor 6	pleckstrin homology and FYVE domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Nucleolus NuA4 Histone Acetyltransferase Complex MOZ/MORF Histone Acetyltransferase Complex NuA3a Histone Acetyltransferase Complex NuA3b Histone Acetyltransferase Complex	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane
	Molecular Function	Protein Binding Histone Acetyltransferase Activity (H3-K23 Specific)	Protein Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Histone H2A Acetylation Histone H3-K23 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Histone H3-K14 Acetylation Regulation Of Signal Transduction By P53 Class Mediator	Protein Transport
Pathways		HATs acetylate histones HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045)	Radiation response ( 20923822)
Interacting Genes		7 interacting genes: CCDC85B FXR2 L3MBTL2 LDOC1 MRGBP PLEKHF2 TRIM54	71 interacting genes: ACY3 AIDA AIMP2 APP APPL1 ARL14EP BEND7 BLOC1S6 BSCL2 CAVIN2 CCDC172 CCDC85B CEP44 CGGBP1 CHIC2 DPPA4 DRAP1 DTX2 DUT ESRP1 FBXO28 FHL3 FOXA1 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HEY1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NKG7 NONO NPM2 PDP1 PEX2 PRDM14 PRKAR1A PRPSAP1 RAB39A RABAC1 RADX RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SPEF1 TBX3 TCN2 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z USF1 ZNF250 ZNF263 ZNF398
Entrez ID		64769	79666
HPRD ID		13347	15147
Ensembl ID		ENSG00000163875	ENSG00000175895
Uniprot IDs		Q9HAF1	Q9H8W4
PDB IDs
Enriched GO Terms of Interacting Partners?
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