PJA1 and OTUB2

Number of citations of the paper that reports this interaction (PubMedID 22626734)
5

Data Source:
BioGRID (enzymatic study)

		PJA1	OTUB2
Description		praja ring finger ubiquitin ligase 1	OTU deubiquitinase, ubiquitin aldehyde binding 2
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GO Annotations	Cellular Component	Cytoplasm	Nucleus
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding NEDD8-specific Protease Activity Ubiquitin Binding
	Biological Process	Protein Ubiquitination Protein Catabolic Process	Protein Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body mass index ( 29273807) Schizophrenia ( 25056061 29483656)
Interacting Genes		64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3A GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440	35 interacting genes: APP ARRDC3 CPSF6 FAM168A GLI2 KRT31 KRT40 LZTS2 MAGEA11 MID1 MID2 PJA1 RBCK1 REL RFFL RNF126 SIAH1 TP53BP2 TRAF6 TRIM2 TRIM25 TRIM26 TRIM27 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIM8 TRIP6 U2AF2 UBC UBE2N USP21 USP28
Entrez ID		64219	78990
HPRD ID		02335	07620
Ensembl ID		ENSG00000181191	ENSG00000089723
Uniprot IDs		Q8NG27	Q96DC9
PDB IDs		2L0B	1TFF 4FJV
Enriched GO Terms of Interacting Partners?
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