PJA1 and USP20

Number of citations of the paper that reports this interaction (PubMedID 22626734)
5

Data Source:
BioGRID (enzymatic study)

		PJA1	USP20
Description		praja ring finger ubiquitin ligase 1	ubiquitin specific peptidase 20
Image
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Centrosome Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	G Protein-coupled Receptor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Thiol-dependent Ubiquitinyl Hydrolase Activity
	Biological Process	Protein Ubiquitination Protein Catabolic Process	Ubiquitin-dependent Protein Catabolic Process Endocytosis Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Ub-specific processing proteases
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body mass index ( 29273807) Schizophrenia ( 25056061 29483656)	Metabolite levels ( 23823483)
Interacting Genes		64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3A GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440	28 interacting genes: ALAS1 BEND5 BEND7 CLSPN DIO2 FATE1 GTF2IRD1 HIF1A IHO1 LMNA MAGEA11 MAPK6 MDFI PJA1 PLA2G2A PRKACA PRKCI RAD17 SPRY2 STING1 TRIM23 UBC ULK1 USP15 USP21 USP28 VAPB VHL
Entrez ID		64219	10868
HPRD ID		02335	07505
Ensembl ID		ENSG00000181191	ENSG00000136878
Uniprot IDs		Q8NG27	Q9Y2K6
PDB IDs		2L0B	6KCZ
Enriched GO Terms of Interacting Partners?
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