OTUB2 and MID1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		OTUB2	MID1
Description		OTU deubiquitinase, ubiquitin aldehyde binding 2	midline 1
Image
GO Annotations	Cellular Component	Nucleus	Spindle Cytosol Microtubule Microtubule Associated Complex Cytoplasmic Microtubule
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding NEDD8-specific Protease Activity Ubiquitin Binding	Protein Binding Microtubule Binding Zinc Ion Binding Transferase Activity Enzyme Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Phosphoprotein Binding
	Biological Process	Protein Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination	Microtubule Cytoskeleton Organization Negative Regulation Of Microtubule Depolymerization Pattern Specification Process Positive Regulation Of Stress-activated MAPK Cascade Protein Localization To Microtubule Interferon-gamma-mediated Signaling Pathway
Pathways		Ovarian tumor domain proteases	Interferon gamma signaling
Drugs
Diseases			Opitz-GBBB syndrome
GWAS
Interacting Genes		35 interacting genes: APP ARRDC3 CPSF6 FAM168A GLI2 KRT31 KRT40 LZTS2 MAGEA11 MID1 MID2 PJA1 RBCK1 REL RFFL RNF126 SIAH1 TP53BP2 TRAF6 TRIM2 TRIM25 TRIM26 TRIM27 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIM8 TRIP6 U2AF2 UBC UBE2N USP21 USP28	33 interacting genes: BYSL DYRK4 EHHADH FKBP1A GMCL1 HMG20B HTT IGBP1 MEOX1 MID1IP1 MID2 OTUB2 PAX6 PKN1 PPP2CA PPP2CB PTPA SPAG5 STK36 TCEANC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBTD1
Entrez ID		78990	4281
HPRD ID		07620	02047
Ensembl ID		ENSG00000089723	ENSG00000101871
Uniprot IDs		Q96DC9	A0A024RBV4 A0A087X0X0 A0A087X255 O15344
PDB IDs		1TFF 4FJV	2DQ5 2FFW 2JUN 5IM8
Enriched GO Terms of Interacting Partners?
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