OTUB2 and TRIM26

Number of citations of the paper that reports this interaction (PubMedID 23105109)
16

Data Source:
BioGRID (two hybrid)

		OTUB2	TRIM26
Description		OTU deubiquitinase, ubiquitin aldehyde binding 2	tripartite motif containing 26
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Cellular_component Nucleus Cytosol
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding NEDD8-specific Protease Activity Ubiquitin Binding	DNA Binding Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding
	Biological Process	Protein Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination	Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Viral Release From Host Cell
Pathways		Ovarian tumor domain proteases	Interferon gamma signaling
Drugs
Diseases
GWAS			Anger ( 24489884) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) General cognitive ability ( 29844566) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401) Neuroticism ( 29255261) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 21926974 22883433 30285260) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		35 interacting genes: APP ARRDC3 CPSF6 FAM168A GLI2 KRT31 KRT40 LZTS2 MAGEA11 MID1 MID2 PJA1 RBCK1 REL RFFL RNF126 SIAH1 TP53BP2 TRAF6 TRIM2 TRIM25 TRIM26 TRIM27 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIM8 TRIP6 U2AF2 UBC UBE2N USP21 USP28	20 interacting genes: INCA1 IRF3 LMNA MAGEA6 MNAT1 OTUB2 PHF7 RABEP1 RNF10 RNF126 SUMO2 THAP1 TLE5 TRIM41 UBE2D1 UBE2D2 UBE2D3 USP36 USP39 USP5
Entrez ID		78990	7726
HPRD ID		07620	02901
Ensembl ID		ENSG00000089723	ENSG00000234127
Uniprot IDs		Q96DC9	A0A024RCP3 Q12899
PDB IDs		1TFF 4FJV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?