WRNIP1 and TRIM14

Number of citations of the paper that reports this interaction (PubMedID 29053956)
17

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		WRNIP1	TRIM14
Description		WRN helicase interacting protein 1	tripartite motif containing 14
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nucleus Membrane Perinuclear Region Of Cytoplasm	Mitochondrial Outer Membrane
	Molecular Function	DNA Binding Protein Binding ATP Binding Enzyme Activator Activity ATPase Activity Single-stranded DNA-dependent ATP-dependent DNA Helicase Activity Identical Protein Binding Metal Ion Binding	Molecular_function Zinc Ion Binding
	Biological Process	DNA Synthesis Involved In DNA Repair DNA-dependent DNA Replication Regulation Of DNA Repair Regulation Of DNA-dependent DNA Replication Initiation DNA Duplex Unwinding Positive Regulation Of Catalytic Activity Innate Immune Response	Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS			Multiple sclerosis ( 31604244)
Interacting Genes		12 interacting genes: ABL1 PCNA PIK3R3 PIN1 POLD1 POLD2 POLD4 RIPK1 TOLLIP TRIM14 UBC WRN	52 interacting genes: ABCF3 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H CENPC CSPP1 EIF3G ETFBKMT FAT1 HERC3 ITM2A IVNS1ABP KAT2B KIF3A LAMTOR1 MITD1 MNAT1 MRPL24 NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR2G PPP2R3C RAB5A RAB9A RBM33 RLF RNF125 RNF20 SMARCB1 SMIM3 STK38 TAX1BP1 TMEM167A UBE2B UBE2N UNK WDR35 WRNIP1 ZC4H2 ZFP36L2 ZNF652
Entrez ID		56897	9830
HPRD ID		10494	05948
Ensembl ID		ENSG00000124535	ENSG00000106785
Uniprot IDs		Q96S55	A0A024R165 Q14142
PDB IDs		3VHS 3VHT
Enriched GO Terms of Interacting Partners?
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