ITSN2 and SYNJ2

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ITSN2	SYNJ2
Description		intersectin 2	synaptojanin 2
Image
GO Annotations	Cellular Component	Cytoplasm Centrosome Extracellular Exosome	Cytosol Cytoskeleton Plasma Membrane Cell Junction Cell Projection Membrane Raft Perinuclear Region Of Cytoplasm Presynapse
	Molecular Function	SH3/SH2 Adaptor Activity Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding	RNA Binding Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Binding SH3 Domain Binding PDZ Domain Binding
	Biological Process	Endocytosis Positive Regulation Of Signal Transduction Viral Process Positive Regulation Of Dendrite Extension	Phosphatidylinositol Biosynthetic Process Brain Development Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation Membrane Organization
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Synthesis of PIPs at the plasma membrane Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Asthma ( 29273806) Chromium levels ( 26025379) Diffuse large B cell lymphoma ( 25261932) Feeling fed-up ( 29500382) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309) SjÃ¶gren's syndrome ( 24097067)	Cannabis use (initiation) ( 22823124) Gamma glutamyl transferase levels ( 29403010) Intraocular pressure ( 29617998) Lipoprotein (a) levels ( 26377243)
Interacting Genes		77 interacting genes: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DNM2 DST EGFR EPS15L1 EPS8 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREM2 GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RABEP1 RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO UBC WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1	6 interacting genes: GRB2 ITSN1 ITSN2 NCK1 RAC1 SYNJ2BP
Entrez ID		50618	8871
HPRD ID		09193	10259
Ensembl ID		ENSG00000198399	ENSG00000078269
Uniprot IDs		A6H8W8 Q9NZM3	A0A1W2PR85 B4DG94 O15056
PDB IDs		1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY 4IIO	1UFW
Enriched GO Terms of Interacting Partners?
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