SYNJ2 and SYNJ2BP

Number of citations of the paper that reports this interaction (PubMedID 10357812)
49

Data Source:
HPRD (in vitro, in vivo)

		SYNJ2	SYNJ2BP
Description		synaptojanin 2	synaptojanin 2 binding protein
Image
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Cell Junction Cell Projection Membrane Raft Perinuclear Region Of Cytoplasm Presynapse	Mitochondrion Ionotropic Glutamate Receptor Complex Basolateral Plasma Membrane Cell Junction Integral Component Of Mitochondrial Outer Membrane Neuromuscular Junction Neuron Projection Postsynaptic Density Membrane
	Molecular Function	RNA Binding Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Binding SH3 Domain Binding PDZ Domain Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Brain Development Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation Membrane Organization	Negative Regulation Of Endothelial Cell Proliferation Protein Targeting Rho Protein Signal Transduction Chemical Synaptic Transmission Regulation Of Notch Signaling Pathway Embryo Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Regulation Of Endocytosis Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Intracellular Distribution Of Mitochondria Negative Regulation Of ERK1 And ERK2 Cascade Receptor Localization To Synapse Cell-cell Adhesion Negative Regulation Of Sprouting Angiogenesis
Pathways		Synthesis of PIPs at the plasma membrane Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Cannabis use (initiation) ( 22823124) Gamma glutamyl transferase levels ( 29403010) Intraocular pressure ( 29617998) Lipoprotein (a) levels ( 26377243)	Blood pressure ( 24954895) LDL cholesterol ( 30275531) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		6 interacting genes: GRB2 ITSN1 ITSN2 NCK1 RAC1 SYNJ2BP	13 interacting genes: ACTB ACVR2A ACVR2B APP LRP1 LRP2 LRP8 RALBP1 RPS6KA1 SMOC1 SYNJ2 UBQLN1 USHBP1
Entrez ID		8871	55333
HPRD ID		10259	15455
Ensembl ID		ENSG00000078269	ENSG00000213463
Uniprot IDs		A0A1W2PR85 B4DG94 O15056	A0A024R670 P57105
PDB IDs		1UFW	2ENO 2JIK 2JIN
Enriched GO Terms of Interacting Partners?
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