ITSN2 and DLGAP1

Number of citations of the paper that reports this interaction (PubMedID 22558309)
18

Data Source:
BioGRID (two hybrid)

		ITSN2	DLGAP1
Description		intersectin 2	DLG associated protein 1
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GO Annotations	Cellular Component	Cytoplasm Centrosome Extracellular Exosome	Cellular_component Plasma Membrane Postsynaptic Density Cell Junction
	Molecular Function	SH3/SH2 Adaptor Activity Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding	Protein Binding Protein-containing Complex Binding
	Biological Process	Endocytosis Positive Regulation Of Signal Transduction Viral Process Positive Regulation Of Dendrite Extension	Chemical Synaptic Transmission
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Asthma ( 29273806) Chromium levels ( 26025379) Diffuse large B cell lymphoma ( 25261932) Feeling fed-up ( 29500382) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309) SjÃ¶gren's syndrome ( 24097067)	Alanine aminotransferase levels ( 31219225) Body fat mass ( 28552196) Cardiac Troponin-T levels ( 23247143) Eating disorders ( 22911880) Economic and political preferences (time) ( 22566634) Erythrocyte cadmium concentration in never smokers ( 27005419) Hip circumference adjusted for BMI ( 28552196) Initial alcohol sensitivity ( 30276832) Menarche (age at onset) ( 27182965 25231870) Midgestational circulating levels of PBDEs ( 28235828) Obesity-related traits ( 23251661) Plasma free amino acid levels ( 30659259) Response to fenofibrate (total cholesterol levels) ( 27002377) Trunk fat mass ( 28552196) Upper eyelid sagging severity ( 24869959)
Interacting Genes		77 interacting genes: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DNM2 DST EGFR EPS15L1 EPS8 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREM2 GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RABEP1 RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO UBC WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1	21 interacting genes: APC DLG1 DLG2 DLG3 DLG4 DLGAP2 DLGAP3 DYNLL1 DYNLL2 GRB2 GRIN2A GRIN2C ITSN1 ITSN2 KCNA4 MYO5A SHANK1 SHANK2 SHANK3 SORBS2 TANC1
Entrez ID		50618	9229
HPRD ID		09193	09260
Ensembl ID		ENSG00000198399	ENSG00000170579
Uniprot IDs		A6H8W8 Q9NZM3	A0A0A0MTP4 A8MXQ8 B7Z2J5 O14490 Q6IS01
PDB IDs		1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY 4IIO	5YPO
Enriched GO Terms of Interacting Partners?
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