ITSN2 and PDE4DIP

Number of citations of the paper that reports this interaction (PubMedID 22558309)
18

Data Source:
BioGRID (two hybrid)

		ITSN2	PDE4DIP
Description		intersectin 2	phosphodiesterase 4D interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Extracellular Exosome	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril
	Molecular Function	SH3/SH2 Adaptor Activity Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding	Protein Binding Enzyme Binding Molecular Adaptor Activity
	Biological Process	Endocytosis Positive Regulation Of Signal Transduction Viral Process Positive Regulation Of Dendrite Extension	Cellular Protein-containing Complex Assembly Regulation Of Golgi Organization
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Asthma ( 29273806) Chromium levels ( 26025379) Diffuse large B cell lymphoma ( 25261932) Feeling fed-up ( 29500382) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309) SjÃ¶gren's syndrome ( 24097067)	Capecitabine sensitivity ( 22864933)
Interacting Genes		77 interacting genes: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DNM2 DST EGFR EPS15L1 EPS8 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREM2 GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RABEP1 RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO UBC WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1	76 interacting genes: ADH1B AEN ANKRD11 ARNT2 BYSL C1orf109 CCDC146 CCDC198 CDC5L CDKN1A CHCHD3 CHD1L EGR2 EIF4E2 FAM161A FAM74A4 FCHSD2 FES FHL1 GADD45G GBE1 GFI1B GNRHR2 GOLGA5 GOLGA8EP GOLGA8F HAUS1 IMMT ITSN2 KDM1A KLC3 KLC4 KRAS KRT1 KRT18 KRT31 LAMTOR3 LENG1 LMO4 MIF4GD MTUS2 NAA10 NEFL NEK2 OSGEP PDE4D PEA15 PFDN1 PIAS4 PPP1R18 PRNP PRPF31 RBM8A RTP5 SCNM1 SDCBP SH2D4A SHFL SMN1 SNCA TEAD4 TFIP11 THRB TK1 TMOD4 TNIK TRAF4 UTP14C VAC14 ZBTB38 ZDHHC17 ZFYVE21 ZNF408 ZNF512B ZNF581 ZSCAN26
Entrez ID		50618	9659
HPRD ID		09193	10482
Ensembl ID		ENSG00000198399	ENSG00000178104
Uniprot IDs		A6H8W8 Q9NZM3	A0A075B749 A0A087WYE4 Q5VU43
PDB IDs		1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY 4IIO
Enriched GO Terms of Interacting Partners?
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