OTX1 and CHRD

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		OTX1	CHRD
Description		orthodenticle homeobox 1	chordin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Extracellular Space
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Protein Binding Heparin Binding Cytokine Binding Syndecan Binding
	Biological Process	Anterior/posterior Pattern Specification Metencephalon Development Midbrain Development Inner Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Diencephalon Morphogenesis	Skeletal System Development Osteoblast Differentiation Gastrulation With Mouth Forming Second Mesoderm Formation Positive Regulation Of Mesenchymal Cell Proliferation BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Negative Regulation Of Cell Migration Negative Regulation Of BMP Signaling Pathway Forebrain Development Floor Plate Development Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Cell Adhesion
Pathways
Drugs
Diseases
GWAS		Neurociticism ( 29500382) Regular attendance at a religious group ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258)	Diisocyanate-induced asthma ( 25918132) Platelet count ( 20139978) Plateletcrit ( 27863252)
Interacting Genes		47 interacting genes: ADAMTSL4 CHIC2 CHRD COMP DPY30 FBLN5 GEMIN8P4 GRN KCNK16 KRT81 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE4A MDFI MGAT5B MTNR1B RBPMS RGS17 RGS20 SMARCC1 SPRY1 SPRY2 TLE4 TNS2 VWC2L	26 interacting genes: ATN1 BMP1 BMP2 CATSPER1 CD36 F2R HOXA1 HRG KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 KRTAP9-2 MEOX2 NOTCH2NLA NR0B2 OTX1 PLSCR1 SMAD3 SPRY2 TLL1 TWSG1
Entrez ID		5013	8646
HPRD ID		08964	04592
Ensembl ID		ENSG00000115507	ENSG00000090539
Uniprot IDs		P32242	E7ESX1 Q8N2W7 Q9H2X0
PDB IDs
Enriched GO Terms of Interacting Partners?
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