OTX1 and TNS2

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		OTX1	TNS2
Description		orthodenticle homeobox 1	tensin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Cell Plasma Membrane Focal Adhesion
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Protein Tyrosine Phosphatase Activity Protein Binding Kinase Binding Metal Ion Binding
	Biological Process	Anterior/posterior Pattern Specification Metencephalon Development Midbrain Development Inner Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Diencephalon Morphogenesis	Kidney Development Negative Regulation Of Cell Proliferation Response To Muscle Activity Cellular Homeostasis Collagen Metabolic Process Multicellular Organism Growth Peptidyl-tyrosine Dephosphorylation Intracellular Signal Transduction Negative Regulation Of Insulin Receptor Signaling Pathway Multicellular Organismal Homeostasis
Pathways
Drugs
Diseases
GWAS		Neurociticism ( 29500382) Regular attendance at a religious group ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		47 interacting genes: ADAMTSL4 CHIC2 CHRD COMP DPY30 FBLN5 GEMIN8P4 GRN KCNK16 KRT81 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE4A MDFI MGAT5B MTNR1B RBPMS RGS17 RGS20 SMARCC1 SPRY1 SPRY2 TLE4 TNS2 VWC2L	86 interacting genes: ADCK5 AMMECR1 AP1S2 ASB3 AXL BRCA1 C11orf87 COX6B2 CSNK1E DCAF11 DCAF8 DDIT4L DLC1 DOK3 EPB41L4A EPS8L2 ERBB2 ERBB3 FABP7 FAM114A1 FGF21 FGFR1 FOXO1 GATA1 GBA3 GFI1B HUWE1 ID2 IHO1 ITGB3 ITGB5 ITGB7 KIF1A KPRP KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP13-1 KRTAP23-1 KRTAP3-1 MPEG1 MT2A MTDH MYBPHL MYH7B NMU NT5C NUBP2 OBSL1 OTX1 PER1 PKP1 PLB1 PLK3 POLR3F RBPMS REEP6 REL RFT1 RNF6 SDCCAG8 SH2B3 SHFL SPATA12 SPRY2 SPRY4 SUV39H1 TBC1D16 TCP10L TEKT5 TENT5A TLE5 TM4SF19 TSC1 TWSG1 WDFY3 ZNF250 ZNF417 ZNF586 ZNF587 ZNF655 ZNF688 ZNRD1
Entrez ID		5013	23371
HPRD ID		08964	16256
Ensembl ID		ENSG00000115507	ENSG00000111077
Uniprot IDs		P32242	A0A024RB48 Q63HR2
PDB IDs			2DKQ 2KNO 2L6K 2LOZ 3HQC
Enriched GO Terms of Interacting Partners?
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