OTX1 and KRT81

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		OTX1	KRT81
Description		orthodenticle homeobox 1	keratin 81
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Extracellular Space Cytosol Keratin Filament
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Protein Binding
	Biological Process	Anterior/posterior Pattern Specification Metencephalon Development Midbrain Development Inner Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Diencephalon Morphogenesis	Keratinization Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases			Monilethrix
GWAS		Neurociticism ( 29500382) Regular attendance at a religious group ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258)	Diisocyanate-induced asthma ( 25918132)
Interacting Genes		47 interacting genes: ADAMTSL4 CHIC2 CHRD COMP DPY30 FBLN5 GEMIN8P4 GRN KCNK16 KRT81 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE4A MDFI MGAT5B MTNR1B RBPMS RGS17 RGS20 SMARCC1 SPRY1 SPRY2 TLE4 TNS2 VWC2L	7 interacting genes: KRT15 KRT31 KRT38 KRT40 KXD1 OTX1 SKIL
Entrez ID		5013	3887
HPRD ID		08964	03691
Ensembl ID		ENSG00000115507	ENSG00000205426
Uniprot IDs		P32242	Q14533
PDB IDs
Enriched GO Terms of Interacting Partners?
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