OTX1 and VWC2L

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		OTX1	VWC2L
Description		orthodenticle homeobox 1	von Willebrand factor C domain containing 2 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Extracellular Space Cell Junction AMPA Glutamate Receptor Complex Synapse
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Protein Binding
	Biological Process	Anterior/posterior Pattern Specification Metencephalon Development Midbrain Development Inner Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Diencephalon Morphogenesis	Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Neuron Differentiation
Pathways
Drugs
Diseases
GWAS		Neurociticism ( 29500382) Regular attendance at a religious group ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Degraded stimulus continuous performance test score ( 31596458) Household income (MTAG) ( 31844048) Neuroticism ( 29255261) PR interval ( 23534349)
Interacting Genes		47 interacting genes: ADAMTSL4 CHIC2 CHRD COMP DPY30 FBLN5 GEMIN8P4 GRN KCNK16 KRT81 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE4A MDFI MGAT5B MTNR1B RBPMS RGS17 RGS20 SMARCC1 SPRY1 SPRY2 TLE4 TNS2 VWC2L	2 interacting genes: FHL3 OTX1
Entrez ID		5013	402117
HPRD ID		08964	19160
Ensembl ID		ENSG00000115507	ENSG00000174453
Uniprot IDs		P32242	B2RUY7 B7ZW27
PDB IDs
Enriched GO Terms of Interacting Partners?
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