TNS2 and WDFY3

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		TNS2	WDFY3
Description		tensin 2	WD repeat and FYVE domain containing 3
Image
GO Annotations	Cellular Component	Cell Plasma Membrane Focal Adhesion	Nuclear Envelope Nucleoplasm Nucleolus Cytoplasm Autophagosome Cytosol Plasma Membrane Inclusion Body PML Body Extrinsic Component Of Membrane Axon Nuclear Membrane Atg12-Atg5-Atg16 Complex Perikaryon Extrinsic Component Of Autophagosome Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Kinase Binding Metal Ion Binding	Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity Protein Binding 1-phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Kidney Development Negative Regulation Of Cell Proliferation Response To Muscle Activity Cellular Homeostasis Collagen Metabolic Process Multicellular Organism Growth Peptidyl-tyrosine Dephosphorylation Intracellular Signal Transduction Negative Regulation Of Insulin Receptor Signaling Pathway Multicellular Organismal Homeostasis	Multicellular Organism Development Aggrephagy
Pathways
Drugs
Diseases
GWAS			Cerebral amyloid deposition (PET imaging) ( 26252872) Oropharynx cancer ( 27749845)
Interacting Genes		86 interacting genes: ADCK5 AMMECR1 AP1S2 ASB3 AXL BRCA1 C11orf87 COX6B2 CSNK1E DCAF11 DCAF8 DDIT4L DLC1 DOK3 EPB41L4A EPS8L2 ERBB2 ERBB3 FABP7 FAM114A1 FGF21 FGFR1 FOXO1 GATA1 GBA3 GFI1B HUWE1 ID2 IHO1 ITGB3 ITGB5 ITGB7 KIF1A KPRP KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP13-1 KRTAP23-1 KRTAP3-1 MPEG1 MT2A MTDH MYBPHL MYH7B NMU NT5C NUBP2 OBSL1 OTX1 PER1 PKP1 PLB1 PLK3 POLR3F RBPMS REEP6 REL RFT1 RNF6 SDCCAG8 SH2B3 SHFL SPATA12 SPRY2 SPRY4 SUV39H1 TBC1D16 TCP10L TEKT5 TENT5A TLE5 TM4SF19 TSC1 TWSG1 WDFY3 ZNF250 ZNF417 ZNF586 ZNF587 ZNF655 ZNF688 ZNRD1	15 interacting genes: ATG5 CEP76 GABARAPL1 GABARAPL2 GRB2 MAP1LC3C MDFI PRMT1 PRMT6 RABGAP1L STAT3 SUV39H1 TNS2 TRIM39 ZBTB44
Entrez ID		23371	23001
HPRD ID		16256	10304
Ensembl ID		ENSG00000111077	ENSG00000163625
Uniprot IDs		A0A024RB48 Q63HR2	A0A024RDC2 Q8IZQ1
PDB IDs		2DKQ 2KNO 2L6K 2LOZ 3HQC	3WIM
Enriched GO Terms of Interacting Partners?
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