TRIM42 and L3MBTL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM42	L3MBTL2
Description		tripartite motif containing 42	L3MBTL histone methyl-lysine binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding
	Biological Process		Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways			SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Bipolar disorder (body mass index interaction) ( 24322204) Refractive astigmatism ( 25367360)	Adventurousness ( 30643258) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Schizophrenia ( 25056061 29483656)
Interacting Genes		64 interacting genes: ADAMTSL4 ARMC7 ARNT2 ARRDC3 AXIN1 BEX2 C1orf109 CARD9 CBY2 CCDC33 CDCA7L CEP70 EFHC2 EMD GLI1 GLRX3 GLYCTK GOLGA2 HOXA1 IHO1 IKZF3 IQUB KCTD9 KLHL38 KRT13 KRT15 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-2 L3MBTL2 LONRF1 LZTS2 MAGOHB MEOX2 MFAP1 MID2 MTUS2 MVP NOTCH2NLA PLSCR1 PNMA1 PSMA1 PSMD9 PTGER3 RAMAC RCOR3 RUNX1T1 SCNM1 SSX2IP STK16 TASOR2 TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VPS37A YWHAQ ZBTB1	17 interacting genes: BEND7 CYB5R3 H3C1 H4C1 LNX2 MEAF6 MPP3 PAICS PHF10 PIAS1 STAC3 STAM2 TBC1D9B TLE5 TRIM42 ZFP64 ZFY
Entrez ID		287015	83746
HPRD ID		15559	13954
Ensembl ID		ENSG00000155890	ENSG00000100395
Uniprot IDs		Q8IWZ5	A0A0S2Z5X6 Q969R5
PDB IDs			2W0T 3CEY 3F70
Enriched GO Terms of Interacting Partners?
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