TRIM42 and RUNX1T1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM42	RUNX1T1
Description		tripartite motif containing 42	RUNX1 partner transcriptional co-repressor 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Nuclear Matrix
	Molecular Function	Protein Binding Zinc Ion Binding	DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process		Generation Of Precursor Metabolites And Energy Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases			Acute myeloid leukemia (AML)
GWAS		Bipolar disorder (body mass index interaction) ( 24322204) Refractive astigmatism ( 25367360)	Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Intelligence (MTAG) ( 29326435) Number of sexual partners ( 30643258) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Plasma anti-thyroglobulin levels ( 29678681) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		64 interacting genes: ADAMTSL4 ARMC7 ARNT2 ARRDC3 AXIN1 BEX2 C1orf109 CARD9 CBY2 CCDC33 CDCA7L CEP70 EFHC2 EMD GLI1 GLRX3 GLYCTK GOLGA2 HOXA1 IHO1 IKZF3 IQUB KCTD9 KLHL38 KRT13 KRT15 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-2 L3MBTL2 LONRF1 LZTS2 MAGOHB MEOX2 MFAP1 MID2 MTUS2 MVP NOTCH2NLA PLSCR1 PNMA1 PSMA1 PSMD9 PTGER3 RAMAC RCOR3 RUNX1T1 SCNM1 SSX2IP STK16 TASOR2 TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VPS37A YWHAQ ZBTB1	52 interacting genes: ABI3 ATN1 BCL6 BRCA1 C19orf57 CBFA2T3 CBY2 CEP170P1 CPSF7 CREB3L1 DNMT1 EFHC2 EPS8 ETS1 GFI1 GSE1 HDAC1 HDAC3 HDAC8 HOMER3 HSP90AA1 ID1 ID3 IHO1 KPNA1 KPNB1 LPXN LZTS2 MEOX2 MID2 NCOR1 NCOR2 NECAB2 NEUROG1 PCBD2 PRKAR2A SIN3A SPEN SPRY2 STX11 TAF9B TAL2 TCF12 TCF3 TCF4 TRIM42 UBQLN4 VDR WBP11 ZBTB16 ZMYM4 ZNF652
Entrez ID		287015	862
HPRD ID		15559	00590
Ensembl ID		ENSG00000155890	ENSG00000079102
Uniprot IDs		Q8IWZ5	A0A087WWT6 A0A0A0MSU1 B2R6I9 Q06455 W8FW32
PDB IDs			1WQ6 2DJ8 2H7B 2KNH 2KYG 2OD1 2ODD 2PP4 4JOL
Enriched GO Terms of Interacting Partners?
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