STX12 and DTX2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		STX12	DTX2
Description		syntaxin 12	deltex E3 ubiquitin ligase 2
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GO Annotations	Cellular Component	Golgi Membrane Phagophore Assembly Site Synaptic Vesicle Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane BLOC-1 Complex SNARE Complex Early Endosome Membrane Vesicle Membrane Raft Phagocytic Vesicle Recycling Endosome Membrane Postsynaptic Recycling Endosome	Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Vesicle Fusion Cholesterol Efflux Vesicle Docking Protein Stabilization	Notch Signaling Pathway Protein Ubiquitination
Pathways			Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS
Interacting Genes		12 interacting genes: BLOC1S6 DNAJC5 DTX2 EEA1 EPB42 HOMER1 LMNA NAPA NSG1 SNAP23 SNAP25 SNAP29	44 interacting genes: ABHD16A ALKBH4 ARNT2 C1orf94 COQ8A DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS1 RBPMS RFX6 RHOXF2 RIMBP3 RUNX1 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1 ZNF641
Entrez ID		23673	113878
HPRD ID		06059	16841
Ensembl ID		ENSG00000117758	ENSG00000091073
Uniprot IDs		Q86Y82	Q86UW9
PDB IDs		2DNX	6IR0
Enriched GO Terms of Interacting Partners?
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