STX12 and EEA1

Number of citations of the paper that reports this interaction (PubMedID 10458612)
161

Data Source:
HPRD (in vitro)

		STX12	EEA1
Description		syntaxin 12	early endosome antigen 1
Image
GO Annotations	Cellular Component	Golgi Membrane Phagophore Assembly Site Synaptic Vesicle Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane BLOC-1 Complex SNARE Complex Early Endosome Membrane Vesicle Membrane Raft Phagocytic Vesicle Recycling Endosome Membrane Postsynaptic Recycling Endosome	Cytoplasm Early Endosome Cytosol Serine-pyruvate Aminotransferase Complex Membrane Extrinsic Component Of Plasma Membrane Early Endosome Membrane Axonal Spine Recycling Endosome Extracellular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	Nucleic Acid Binding Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Zinc Ion Binding GTP-dependent Protein Binding Protein Homodimerization Activity
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Vesicle Fusion Cholesterol Efflux Vesicle Docking Protein Stabilization	Endocytosis Vesicle Fusion Synaptic Vesicle To Endosome Fusion Viral RNA Genome Replication Early Endosome To Late Endosome Transport
Pathways			Toll Like Receptor 9 (TLR9) Cascade
Drugs			Inositol 1,3-Bisphosphate
Diseases
GWAS			Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Sensorimotor dexterity ( 31596458) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Western dietary pattern ( 28644415)
Interacting Genes		12 interacting genes: BLOC1S6 DNAJC5 DTX2 EEA1 EPB42 HOMER1 LMNA NAPA NSG1 SNAP23 SNAP25 SNAP29	13 interacting genes: IGF1R MAPK14 RAB22A RAB31 RAB5A RAB5B RAB5C RRAD STX12 STX6 TOM1 USO1 ZFYVE16
Entrez ID		23673	8411
HPRD ID		06059	05460
Ensembl ID		ENSG00000117758	ENSG00000102189
Uniprot IDs		Q86Y82	Q15075
PDB IDs		2DNX	1HYI 1HYJ 1JOC 3MJH
Enriched GO Terms of Interacting Partners?
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