CBY2 and GRAP2

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		CBY2	GRAP2
Description		chibby family member 2	GRB2 related adaptor protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Vesicle	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Plasma Membrane
	Molecular Function	Protein Binding	SH3/SH2 Adaptor Activity Protein Binding
	Biological Process		Ras Protein Signal Transduction Cell-cell Signaling Positive Regulation Of Signal Transduction T Cell Costimulation Fc-epsilon Receptor Signaling Pathway T Cell Receptor Signaling Pathway
Pathways			Signaling by SCF-KIT Generation of second messenger molecules DAP12 signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization CD28 co-stimulation
Drugs
Diseases
GWAS			Body mass index ( 26426971) Systemic lupus erythematosus ( 28714469)
Interacting Genes		76 interacting genes: ACTN1 ARHGEF40 ARMC7 C19orf44 C1orf109 CCDC146 CCDC198 CCHCR1 CCNG1 CDC23 CDK2 CEP44 CEP57L1 CEP95 CHCHD3 CHIC2 CKS1B CNNM3 DGCR6 DUSP14 DZIP1L EIF4E2 ELOA ENKD1 FAM161A FANCG FRS3 GADD45A GOLGA2 GOLGA6L2 GRAP2 HAUS1 KIFC3 KLC3 LATS1 LENG1 LMO1 LMO2 LMO3 LNX1 MED28 METTL17 MLH1 MMAB MOS NDUFA5 NINL NTAQ1 PID1 PIN1 PLEKHN1 POLR1C PPP1R18 PRPF31 RNF6 RPL9 RTP5 RUNX1T1 SCNM1 SDCBP SH3RF2 SYCE1 TCEANC TEX11 TRIM42 TSC2 TSGA10 TUBGCP4 TXLNA TXLNB ZC2HC1C ZMAT2 ZNF564 ZNF581 ZNF655 ZNF688	66 interacting genes: BAG4 BEND5 BLNK CBL CBLB CBY2 CCHCR1 CCNDBP1 CD28 COG6 CSF1R DNM2 DVL2 EGFR ETV5 FASLG GAB1 GAB2 GAB3 GAREM1 GATA1 GFAP GOLGA2 GRB2 HNRNPK IHO1 IKZF3 KHDRBS1 KHDRBS2 KIT KRT13 KRTAP1-3 KRTAP4-11 KRTAP4-12 LAT LATS2 LAX1 LCP2 LNX1 LNX2 MAGED1 MAP4K1 MKRN3 MTUS2 PNMA1 PRPH2 RACK1 RBPMS RBX1 RIN3 RINT1 SHB SHC1 SOS2 SPRY2 SSX2IP STAMBP TFIP11 TLE5 TRAF1 TSNAXIP1 USP8 WWP2 YWHAE ZBTB7B ZNF526
Entrez ID		220082	9402
HPRD ID		14856	05156
Ensembl ID		ENSG00000174015	ENSG00000100351
Uniprot IDs		A0A140VJV5 Q8NA61	B7Z8E3 O75791 Q6FI14
PDB IDs			5GJH
Enriched GO Terms of Interacting Partners?
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