CBY2 and RNF6

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		CBY2	RNF6
Description		chibby family member 2	ring finger protein 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Vesicle	Nucleus Cytoplasm PML Body Axon Nuclear Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Androgen Receptor Binding Ubiquitin Protein Ligase Activity
	Biological Process		Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Axon Extension Protein K27-linked Ubiquitination Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway Protein K48-linked Ubiquitination Protein K6-linked Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Sporadic pituitary adenoma ( 26029870) Type 2 diabetes ( 24509480 30297969 30718926 28869590) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		76 interacting genes: ACTN1 ARHGEF40 ARMC7 C19orf44 C1orf109 CCDC146 CCDC198 CCHCR1 CCNG1 CDC23 CDK2 CEP44 CEP57L1 CEP95 CHCHD3 CHIC2 CKS1B CNNM3 DGCR6 DUSP14 DZIP1L EIF4E2 ELOA ENKD1 FAM161A FANCG FRS3 GADD45A GOLGA2 GOLGA6L2 GRAP2 HAUS1 KIFC3 KLC3 LATS1 LENG1 LMO1 LMO2 LMO3 LNX1 MED28 METTL17 MLH1 MMAB MOS NDUFA5 NINL NTAQ1 PID1 PIN1 PLEKHN1 POLR1C PPP1R18 PRPF31 RNF6 RPL9 RTP5 RUNX1T1 SCNM1 SDCBP SH3RF2 SYCE1 TCEANC TEX11 TRIM42 TSC2 TSGA10 TUBGCP4 TXLNA TXLNB ZC2HC1C ZMAT2 ZNF564 ZNF581 ZNF655 ZNF688	36 interacting genes: AHCYL1 AR CBY2 CCDC33 CCDC57 CEP70 GOLGA2 HOOK2 IKZF1 IKZF3 KIAA0753 KRT15 KRT40 LDOC1 MAGED1 MDFI MEOX2 MID2 MIPOL1 MTUS2 PNMA2 REL RINT1 RPGRIP1 SSX2IP STX11 TADA2A TCF4 TFIP11 TNS2 TRIM23 TRIM27 TRIM37 TSGA10 UBE2D1 UBE2H
Entrez ID		220082	6049
HPRD ID		14856	05027
Ensembl ID		ENSG00000174015	ENSG00000127870
Uniprot IDs		A0A140VJV5 Q8NA61	A0A024RDP2 A0A0S2Z4G9 Q9Y252
PDB IDs
Enriched GO Terms of Interacting Partners?
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