CBY2 and LNX1

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		CBY2	LNX1
Description		chibby family member 2	ligand of numb-protein X 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Vesicle	Cytoplasm
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding
	Biological Process		Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Beard thickness ( 26926045) Cervical artery dissection ( 25420145) DNA methylation (variation) ( 23725790) Heel bone mineral density ( 30598549) Height ( 28552196) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Uterine fibroids ( 30194396 31649266)
Interacting Genes		76 interacting genes: ACTN1 ARHGEF40 ARMC7 C19orf44 C1orf109 CCDC146 CCDC198 CCHCR1 CCNG1 CDC23 CDK2 CEP44 CEP57L1 CEP95 CHCHD3 CHIC2 CKS1B CNNM3 DGCR6 DUSP14 DZIP1L EIF4E2 ELOA ENKD1 FAM161A FANCG FRS3 GADD45A GOLGA2 GOLGA6L2 GRAP2 HAUS1 KIFC3 KLC3 LATS1 LENG1 LMO1 LMO2 LMO3 LNX1 MED28 METTL17 MLH1 MMAB MOS NDUFA5 NINL NTAQ1 PID1 PIN1 PLEKHN1 POLR1C PPP1R18 PRPF31 RNF6 RPL9 RTP5 RUNX1T1 SCNM1 SDCBP SH3RF2 SYCE1 TCEANC TEX11 TRIM42 TSC2 TSGA10 TUBGCP4 TXLNA TXLNB ZC2HC1C ZMAT2 ZNF564 ZNF581 ZNF655 ZNF688	233 interacting genes: ABCA1 ABCB1 ABR ACAT2 ACY3 ADRA1D AGTRAP AIDA AIMP2 AKIRIN2 ALDOC ALKBH3 AMMECR1L APIP APOL4 APP ARHGAP6 ARHGEF16 ARVCF ATPAF2 ATRIP AURKB AURKC BCR BLVRA BPIFA1 C1QTNF1 CA8 CALCOCO2 CAMK2N2 CATSPERD CBY2 CCDC102B CCDC114 CCDC85B CDA CDC42EP4 CEP72 CGN CIB3 CIRBP CITED1 CLDN1 CLDN17 CLDN2 CLK2 COIL CPNE2 CTBP1 CTNND2 CTSO CUTC CXADR DAB1 DAPK1 DCTD DCUN1D5 DDX17 DEPTOR DNPEP DOCK9 DPF2 DVL3 EBF4 EHMT2 EIF4H ENOX1 EPHB3 EXOC8 FAM118A FAM124A FAM9B FBP1 FBXL12 FHL3 GAS2L2 GDI1 GIPR GJD2 GJD4 GOLPH3L GPR142 GRAP2 GRB2 GRIN1 HMBOX1 HOMEZ HSBP1 HTR2B HUNK IGSF5 IL3RA ILF3 INKA2 INSC ISCU JAK3 JOSD1 KALRN KCNA4 KCTD1 KCTD13 KCTD17 KCTD6 KHDRBS3 KLHL12 KRT15 KRTAP4-12 KRTAP4-2 KRTAP9-2 KXD1 LCLAT1 LDOC1 LGALS14 LGR6 LNX2 LRRC3B LSM2 MAGEA11 MAGEB18 MAPK9 MEMO1 METTL21A MRFAP1L1 MRPS24 MTMR9 MTUS2 MUSTN1 MVB12B NADK NAGK NCK2 NECAB2 NEK6 NKD2 NME7 NOTCH2NLA NRCAM NUDT14 NUMB NUP37 NXT2 ORMDL3 OSBP2 OSGIN1 PAFAH1B3 PAICS PBK PBLD PCBD1 PDZRN3 PDZRN4 PKDREJ PKM PKP4 PNMA1 POMGNT1 PPIA PPID PQBP1 PRR13 PTGIR PTPN11 PTS RABAC1 RAD51D RAD54B RASL11B RBMX RBMY1A1 RFPL3 ROBO3 ROPN1 RPIA RPS6KA1 RUFY4 RUVBL2 SAPCD1 SAT1 SCLT1 SDK1 SGF29 SH2D2A SHTN1 SLC6A15 SLC6A5 SNCB SNRNP25 SNRPF SOCS6 SPHKAP SRSF1 SSNA1 SSTR3 STAC2 STOML2 STRN STX5 SUV39H1 SUV39H2 TBCEL THAP7 TIFA TMEM14C TNFRSF18 TPM4 TRAF1 TRAF2 TRIM23 TRIM39 TRIM54 TRIP13 TRMT12 TSC2 TSC22D4 TSSK3 TYRO3 UBE2D2 UBE2N UBE2V2 ULK2 VCP VRK2 WAC WNT8A WWP1 ZADH2 ZBTB43 ZBTB8A ZCCHC10 ZFP64 ZNF581 ZNF593
Entrez ID		220082	84708
HPRD ID		14856	17287
Ensembl ID		ENSG00000174015	ENSG00000072201
Uniprot IDs		A0A140VJV5 Q8NA61	Q8TBB1
PDB IDs			3B76 5H7R 5H7S
Enriched GO Terms of Interacting Partners?
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