ADD1 and SMARCC1

Number of citations of the paper that reports this interaction (PubMedID 17074803)
19

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ADD1	SMARCC1
Description		adducin 1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion F-actin Capping Protein Complex Postsynaptic Density Nuclear Body Plasma Membrane Raft	Nuclear Chromatin XY Body Nucleus Nucleoplasm Cytoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex
	Molecular Function	RNA Binding Actin Binding Structural Molecule Activity Structural Constituent Of Cytoskeleton Calmodulin Binding Transcription Factor Binding Spectrin Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Actin Filament Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding Protein N-terminus Binding
	Biological Process	Cell Morphogenesis In Utero Embryonic Development Cell Volume Homeostasis Hemoglobin Metabolic Process Actin Cytoskeleton Organization Erythrocyte Differentiation Positive Regulation Of Protein Binding Multicellular Organism Growth IRE1-mediated Unfolded Protein Response Homeostasis Of Number Of Cells Within A Tissue Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Transmembrane Transport Cellular Response To Calcium Ion Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Adherens Junction Organization	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Insulin Receptor Signaling Pathway Animal Organ Morphogenesis Prostate Gland Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Caspase-mediated cleavage of cytoskeletal proteins XBP1(S) activates chaperone genes Miscellaneous transport and binding events	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Household income ( 31844048) Household income (MTAG) ( 31844048) Huntington's disease progression ( 28642124)	Household income (MTAG) ( 31844048)
Interacting Genes		21 interacting genes: ADD2 ATP1A1 CALM1 CASP3 CSNK2B GEMIN7 HMG20A HSPH1 ID2 ID3 MAP1LC3B PRKACA PRKCA PRKCD RFX1 ROCK1 SMARCC1 SPTA1 SPTB TK1 ZDHHC17	26 interacting genes: ADAMTSL4 ADD1 AKT1 CCNE1 CEBPB EWSR1 FANCA FUS GATA1 ITCH KLF1 MSL1 MYC NCOA1 NEDD4 NONO NR3C1 OTX1 PLSCR1 PRMT5 RELB SIN3A SMARCA4 SMARCD3 SP1 TAF15
Entrez ID		118	6599
HPRD ID		00036	03435
Ensembl ID		ENSG00000087274	ENSG00000173473
Uniprot IDs		P35611	Q58EY4 Q92922
PDB IDs			2YUS 5GJK
Enriched GO Terms of Interacting Partners?
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