ADD1 and ID3

Number of citations of the paper that reports this interaction (PubMedID 10585876)
25

Data Source:
HPRD (in vitro)

		ADD1	ID3
Description		adducin 1	inhibitor of DNA binding 3, HLH protein
Image		No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion F-actin Capping Protein Complex Postsynaptic Density Nuclear Body Plasma Membrane Raft	Nucleus
	Molecular Function	RNA Binding Actin Binding Structural Molecule Activity Structural Constituent Of Cytoskeleton Calmodulin Binding Transcription Factor Binding Spectrin Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Actin Filament Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Protein Dimerization Activity Transcription Regulator Activity Leptomycin B Binding
	Biological Process	Cell Morphogenesis In Utero Embryonic Development Cell Volume Homeostasis Hemoglobin Metabolic Process Actin Cytoskeleton Organization Erythrocyte Differentiation Positive Regulation Of Protein Binding Multicellular Organism Growth IRE1-mediated Unfolded Protein Response Homeostasis Of Number Of Cells Within A Tissue Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Transmembrane Transport Cellular Response To Calcium Ion Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Adherens Junction Organization	Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Regulation Of DNA Replication Multicellular Organism Development Central Nervous System Development Heart Development Muscle Organ Development Response To Wounding Positive Regulation Of Gene Expression Cell Differentiation Epithelial Cell Differentiation Notochord Development Circadian Regulation Of Gene Expression Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Cellular Response To Leptomycin B Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		Caspase-mediated cleavage of cytoskeletal proteins XBP1(S) activates chaperone genes Miscellaneous transport and binding events	NGF-stimulated transcription
Drugs
Diseases
GWAS		Household income ( 31844048) Household income (MTAG) ( 31844048) Huntington's disease progression ( 28642124)
Interacting Genes		21 interacting genes: ADD2 ATP1A1 CALM1 CASP3 CSNK2B GEMIN7 HMG20A HSPH1 ID2 ID3 MAP1LC3B PRKACA PRKCA PRKCD RFX1 ROCK1 SMARCC1 SPTA1 SPTB TK1 ZDHHC17	37 interacting genes: ADD1 ATF3 CBFA2T2 CDK2 CEP350 CNOT3 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 GATA4 GNB2 GTF2A1L HES1 ID4 IFI16 IKBKG MLX MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626
Entrez ID		118	3399
HPRD ID		00036	02608
Ensembl ID		ENSG00000087274	ENSG00000117318
Uniprot IDs		P35611	Q02535
PDB IDs			2LFH
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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