ADD1 and GEMIN7

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		ADD1	GEMIN7
Description		adducin 1	gem nuclear organelle associated protein 7
Image		No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion F-actin Capping Protein Complex Postsynaptic Density Nuclear Body Plasma Membrane Raft	Nucleoplasm Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	RNA Binding Actin Binding Structural Molecule Activity Structural Constituent Of Cytoskeleton Calmodulin Binding Transcription Factor Binding Spectrin Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Actin Filament Binding	Protein Binding
	Biological Process	Cell Morphogenesis In Utero Embryonic Development Cell Volume Homeostasis Hemoglobin Metabolic Process Actin Cytoskeleton Organization Erythrocyte Differentiation Positive Regulation Of Protein Binding Multicellular Organism Growth IRE1-mediated Unfolded Protein Response Homeostasis Of Number Of Cells Within A Tissue Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Transmembrane Transport Cellular Response To Calcium Ion Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Adherens Junction Organization	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Import Into Nucleus
Pathways		Caspase-mediated cleavage of cytoskeletal proteins XBP1(S) activates chaperone genes Miscellaneous transport and binding events	snRNP Assembly
Drugs
Diseases
GWAS		Household income ( 31844048) Household income (MTAG) ( 31844048) Huntington's disease progression ( 28642124)	Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		21 interacting genes: ADD2 ATP1A1 CALM1 CASP3 CSNK2B GEMIN7 HMG20A HSPH1 ID2 ID3 MAP1LC3B PRKACA PRKCA PRKCD RFX1 ROCK1 SMARCC1 SPTA1 SPTB TK1 ZDHHC17	20 interacting genes: ADD1 CEP126 EDRF1 FEZ1 GEMIN6 GOLM1 KAT5 RN7SL1 RNU1-1 RNU2-1 RPLP1 SHC1 SMN1 SNRPB SNRPD2 SNRPD3 SNRPE STRAP TAOK1 TUBA1A
Entrez ID		118	79760
HPRD ID		00036	07600
Ensembl ID		ENSG00000087274	ENSG00000142252
Uniprot IDs		P35611	Q9H840
PDB IDs			1Y96
Enriched GO Terms of Interacting Partners?
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