SMARCC1 and TAF15

Number of citations of the paper that reports this interaction (PubMedID 30962207)
2

Data Source:
BioGRID (pull down)

		SMARCC1	TAF15
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1	TATA-box binding protein associated factor 15
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GO Annotations	Cellular Component	Nuclear Chromatin XY Body Nucleus Nucleoplasm Cytoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding Protein N-terminus Binding	DNA Binding Transcription Coregulator Activity RNA Binding MRNA 3'-UTR Binding Protein Binding Metal Ion Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Insulin Receptor Signaling Pathway Animal Organ Morphogenesis Prostate Gland Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter RNA Splicing Positive Regulation Of Transcription, DNA-templated MRNA Stabilization Regulation Of Signal Transduction By P53 Class Mediator
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases			Extraskeletal myxoid chondrosarcoma
GWAS		Household income (MTAG) ( 31844048)	Blood protein levels ( 28240269) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		26 interacting genes: ADAMTSL4 ADD1 AKT1 CCNE1 CEBPB EWSR1 FANCA FUS GATA1 ITCH KLF1 MSL1 MYC NCOA1 NEDD4 NONO NR3C1 OTX1 PLSCR1 PRMT5 RELB SIN3A SMARCA4 SMARCD3 SP1 TAF15	22 interacting genes: ARID1A CACNA1A H2AC20 H3-4 H3C1 H4C14 POLR2C POLR2E POLR2G PRMT8 SAFB SF1 SMARCA4 SMARCC1 SMARCC2 TAF1 TAF12 TAF13 TAF5 TAF7 YWHAG ZNF384
Entrez ID		6599	8148
HPRD ID		03435	09031
Ensembl ID		ENSG00000173473	ENSG00000270647
Uniprot IDs		Q58EY4 Q92922	Q92804
PDB IDs		2YUS 5GJK	2MMY
Enriched GO Terms of Interacting Partners?
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