SMARCC1 and KLF1

Number of citations of the paper that reports this interaction (PubMedID 11018012)
80

Data Source:
HPRD (in vitro)

		SMARCC1	KLF1
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1	Kruppel like factor 1
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GO Annotations	Cellular Component	Nuclear Chromatin XY Body Nucleus Nucleoplasm Cytoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Nuclear Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding Protein N-terminus Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Insulin Receptor Signaling Pathway Animal Organ Morphogenesis Prostate Gland Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Erythrocyte Differentiation Positive Regulation Of Transcription, DNA-templated Maternal Process Involved In Female Pregnancy Cellular Response To Peptide
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases			Congenital dyserythropoietic anemias (CDAs)
GWAS		Household income (MTAG) ( 31844048)	Clozapine-induced agranulocytosis ( 25187353) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Mean corpuscular volume ( 29403010 27863252) Red blood cell count ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		26 interacting genes: ADAMTSL4 ADD1 AKT1 CCNE1 CEBPB EWSR1 FANCA FUS GATA1 ITCH KLF1 MSL1 MYC NCOA1 NEDD4 NONO NR3C1 OTX1 PLSCR1 PRMT5 RELB SIN3A SMARCA4 SMARCD3 SP1 TAF15	14 interacting genes: ARID1A CREBBP CSNK2A1 CSNK2A2 EP300 FLI1 HDAC1 PRKACA SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCE1
Entrez ID		6599	10661
HPRD ID		03435	07197
Ensembl ID		ENSG00000173473	ENSG00000105610
Uniprot IDs		Q58EY4 Q92922	Q13351
PDB IDs		2YUS 5GJK	2L2I 2MBH 2N23
Enriched GO Terms of Interacting Partners?
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