ADD1 and RFX1

Number of citations of the paper that reports this interaction (PubMedID 16289097)
5

Data Source:
HPRD (in vivo, two hybrid)

		ADD1	RFX1
Description		adducin 1	regulatory factor X1
Image		No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion F-actin Capping Protein Complex Postsynaptic Density Nuclear Body Plasma Membrane Raft	Nuclear Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Actin Binding Structural Molecule Activity Structural Constituent Of Cytoskeleton Calmodulin Binding Transcription Factor Binding Spectrin Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Actin Filament Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Cell Morphogenesis In Utero Embryonic Development Cell Volume Homeostasis Hemoglobin Metabolic Process Actin Cytoskeleton Organization Erythrocyte Differentiation Positive Regulation Of Protein Binding Multicellular Organism Growth IRE1-mediated Unfolded Protein Response Homeostasis Of Number Of Cells Within A Tissue Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Transmembrane Transport Cellular Response To Calcium Ion Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Adherens Junction Organization	Regulation Of Transcription By RNA Polymerase II Immune Response
Pathways		Caspase-mediated cleavage of cytoskeletal proteins XBP1(S) activates chaperone genes Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Household income ( 31844048) Household income (MTAG) ( 31844048) Huntington's disease progression ( 28642124)
Interacting Genes		21 interacting genes: ADD2 ATP1A1 CALM1 CASP3 CSNK2B GEMIN7 HMG20A HSPH1 ID2 ID3 MAP1LC3B PRKACA PRKCA PRKCD RFX1 ROCK1 SMARCC1 SPTA1 SPTB TK1 ZDHHC17	15 interacting genes: ABL1 ADD1 HIVEP2 HMGB1 MAGED1 NFIB NFIC NFIX PRKACA RFX2 RFX3 SMAD1 SMAD4 SMAD9 TADA3
Entrez ID		118	5989
HPRD ID		00036	02476
Ensembl ID		ENSG00000087274	ENSG00000132005
Uniprot IDs		P35611	P22670
PDB IDs			1DP7
Enriched GO Terms of Interacting Partners?
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