TRIP13 and KYAT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIP13	KYAT1
Description		thyroid hormone receptor interactor 13	kynurenine aminotransferase 1
Image
GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Chromosome	Cytoplasm Mitochondrion Cytosol
	Molecular Function	Transcription Coregulator Activity Protein Binding ATP Binding Identical Protein Binding	Protein Binding Transaminase Activity Kynurenine-oxoglutarate Transaminase Activity Pyridoxal Phosphate Binding Protein Homodimerization Activity Glutamine-phenylpyruvate Transaminase Activity Cysteine-S-conjugate Beta-lyase Activity
	Biological Process	Oocyte Maturation Double-strand Break Repair Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Meiotic Recombination Checkpoint Regulation Of Nucleic Acid-templated Transcription	L-phenylalanine Catabolic Process Tryptophan Catabolic Process Cellular Modified Amino Acid Metabolic Process Cellular Amino Acid Biosynthetic Process Kynurenine Metabolic Process L-kynurenine Catabolic Process
Pathways			Tryptophan catabolism Phenylalanine metabolism Glutamate and glutamine metabolism
Drugs			Pyridoxal Phosphate Pyridoxamine-5'-Phosphate D-Phenylalanine N'-Pyridoxyl-Lysine-5'-Monophosphate 1H-INDOL-3-YLACETIC ACID
Diseases
GWAS		Pancreatic cancer ( 25086665)
Interacting Genes		83 interacting genes: ADAM15 AMDHD2 ARL11 ARSA ASB13 BUB1B C11orf54 C4orf33 CARD14 CD99 CDC20 CFP COMT CRMP1 CRYBA2 CYB5R2 DDAH2 DIP2A DPYSL4 DTX2 FBLN5 FBXO8 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 INTS11 KRTAP12-1 KRTAP12-2 KRTAP26-1 KRTAP3-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MEAK7 METTL15 MFGE8 MGAT5B MORN3 MPPED2 MVP NIF3L1 NME4 NTAQ1 PARP11 PBLD PCMTD2 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 PPP2CA PRKN QARS1 RBPMS RHOXF2 SCP2 SEC24A SELENBP1 SEMA4G SIGLEC5 SMUG1 SPRYD7 STAMBP STAMBPL1 TEX37 THRB TINAGL1 TNRC6A TPT1 UBE2I VDR ZNF34 ZNF655	3 interacting genes: APP TRIP13 VAC14
Entrez ID		9319	883
HPRD ID		05145	02769
Ensembl ID		ENSG00000071539	ENSG00000171097
Uniprot IDs		Q15645	A8K563 B7Z4W5 Q16773
PDB IDs		5VQ9 5VQA 5WC2 6F0X	1W7L 1W7M 1W7N 3FVS 3FVU 3FVX 4WLH 4WLJ 4WP0
Enriched GO Terms of Interacting Partners?
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