TRIP13 and TPT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIP13	TPT1
Description		thyroid hormone receptor interactor 13	tumor protein, translationally-controlled 1
Image
GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Chromosome	Spindle Pole Extracellular Space Cell Nucleus Cytoplasm Multivesicular Body Cytosol Cytoplasmic Microtubule Extracellular Exosome
	Molecular Function	Transcription Coregulator Activity Protein Binding ATP Binding Identical Protein Binding	RNA Binding Calcium Ion Binding Protein Binding
	Biological Process	Oocyte Maturation Double-strand Break Repair Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Meiotic Recombination Checkpoint Regulation Of Nucleic Acid-templated Transcription	Calcium Ion Transport Cellular Calcium Ion Homeostasis Response To Virus Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways
Drugs			Calcium Citrate Calcium Phosphate
Diseases
GWAS		Pancreatic cancer ( 25086665)	Type 2 diabetes ( 25760438)
Interacting Genes		83 interacting genes: ADAM15 AMDHD2 ARL11 ARSA ASB13 BUB1B C11orf54 C4orf33 CARD14 CD99 CDC20 CFP COMT CRMP1 CRYBA2 CYB5R2 DDAH2 DIP2A DPYSL4 DTX2 FBLN5 FBXO8 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 INTS11 KRTAP12-1 KRTAP12-2 KRTAP26-1 KRTAP3-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MEAK7 METTL15 MFGE8 MGAT5B MORN3 MPPED2 MVP NIF3L1 NME4 NTAQ1 PARP11 PBLD PCMTD2 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 PPP2CA PRKN QARS1 RBPMS RHOXF2 SCP2 SEC24A SELENBP1 SEMA4G SIGLEC5 SMUG1 SPRYD7 STAMBP STAMBPL1 TEX37 THRB TINAGL1 TNRC6A TPT1 UBE2I VDR ZNF34 ZNF655	30 interacting genes: APP ATP1A1 ATP1A2 BCL2L1 CALM1 DBN1 EEF1A1 EEF1A2 EEF1B2 EEF1D FANCA HSPB1 IKBKG LIG4 MCL1 MCPH1 MDM2 MLC1 NKX3-1 NOTCH3 PER2 PLK1 RBBP6 RPLP1 SNX6 SPP1 STEAP3 TRIP13 TUBB2A VHL
Entrez ID		9319	7178
HPRD ID		05145	15979
Ensembl ID		ENSG00000071539	ENSG00000133112
Uniprot IDs		Q15645	A0A024RDY2 A0A0B4J2C3 A0A0P1J1R0 P13693
PDB IDs		5VQ9 5VQA 5WC2 6F0X	1YZ1 2HR9 3EBM 4Z9V 5O9L 5O9M
Enriched GO Terms of Interacting Partners?
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