KAT7 and GMNN

Number of citations of the paper that reports this interaction (PubMedID 16428461)
70

Data Source:
BioGRID (enzymatic study)

		KAT7	GMNN
Description		lysine acetyltransferase 7	geminin DNA replication inhibitor
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	DNA Replication Origin Binding DNA-binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Deacetylase Binding Repressing Transcription Factor Binding
	Biological Process	DNA Replication Regulation Of Transcription, DNA-templated Internal Peptidyl-lysine Acetylation Stress-activated Protein Kinase Signaling Cascade Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Sorbitol Response To Hydroxyurea Response To Actinomycin D Response To Dithiothreitol Response To Anisomycin Positive Regulation Of Histone H4 Acetylation Positive Regulation Of Protein Localization To Nucleus	G1/S Transition Of Mitotic Cell Cycle Regulation Of DNA Replication Negative Regulation Of DNA Replication Animal Organ Morphogenesis Positive Regulation Of Chromatin Binding Negative Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated DNA Replication Preinitiation Complex Assembly Negative Regulation Of DNA-dependent DNA Replication
Pathways		HATs acetylate histones	CDT1 association with the CDC6:ORC:origin complex Activation of the pre-replicative complex
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular volume ( 29403010 27863252)	Metabolite levels ( 23823483)
Interacting Genes		43 interacting genes: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP126 CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN H2AC20 H3C1 H4C1 HAP1 HOOK2 ING4 KATNBL1 KCTD13 LRIF1 MAP2K1 MCM2 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPTIN5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165	27 interacting genes: ARNT AURKA CASP3 CDKN1A CDKN2A CDT1 CSNK2A1 FZR1 HOXA10 HOXA11 HOXA7 HOXB7 HOXC8 HOXC9 HOXD10 IMPDH1 KAT7 MCM6 NCF1 PHC1 REPIN1 SCMH1 SIX3 SMARCA4 UBE2C UBE2S ZNF439
Entrez ID		11143	51053
HPRD ID		07135	06783
Ensembl ID		ENSG00000136504	ENSG00000112312
Uniprot IDs		O95251	A0A024QZY7 O75496
PDB IDs		5GK9	1T6F 1UII 2LP0 2WVR 4BRY
Enriched GO Terms of Interacting Partners?
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