KAT7 and ZNF165

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT7	ZNF165
Description		lysine acetyltransferase 7	zinc finger protein 165
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol	Nucleus
	Molecular Function	DNA Replication Origin Binding DNA-binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone Binding	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	DNA Replication Regulation Of Transcription, DNA-templated Internal Peptidyl-lysine Acetylation Stress-activated Protein Kinase Signaling Cascade Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Sorbitol Response To Hydroxyurea Response To Actinomycin D Response To Dithiothreitol Response To Anisomycin Positive Regulation Of Histone H4 Acetylation Positive Regulation Of Protein Localization To Nucleus	Myelination Negative Regulation Of Transcription, DNA-templated
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular volume ( 29403010 27863252)	Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Estimated glomerular filtration rate ( 31451708) Hepcidin/ferritin ratio ( 27846281) Moderate to vigorous physical activity levels ( 29899525) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		43 interacting genes: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP126 CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN H2AC20 H3C1 H4C1 HAP1 HOOK2 ING4 KATNBL1 KCTD13 LRIF1 MAP2K1 MCM2 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPTIN5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165	22 interacting genes: AHCYL1 CCDC130 CCDC85B DVL2 ELOA2 EMD EWSR1 FAM124A GPATCH2L KAT7 KRT40 KRTAP10-3 KRTAP10-7 KRTAP4-12 MID2 PDLIM7 SCAND1 SUV39H1 ZKSCAN8 ZNF24 ZNF250 ZNF446
Entrez ID		11143	7718
HPRD ID		07135	02903
Ensembl ID		ENSG00000136504	ENSG00000197279
Uniprot IDs		O95251	P49910 Q53Z40
PDB IDs		5GK9
Enriched GO Terms of Interacting Partners?
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