KAT7 and RGL2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT7	RGL2
Description		lysine acetyltransferase 7	ral guanine nucleotide dissociation stimulator like 2
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol	Cellular_component
	Molecular Function	DNA Replication Origin Binding DNA-binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone Binding	Ras Guanyl-nucleotide Exchange Factor Activity Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	DNA Replication Regulation Of Transcription, DNA-templated Internal Peptidyl-lysine Acetylation Stress-activated Protein Kinase Signaling Cascade Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Sorbitol Response To Hydroxyurea Response To Actinomycin D Response To Dithiothreitol Response To Anisomycin Positive Regulation Of Histone H4 Acetylation Positive Regulation Of Protein Localization To Nucleus	Ras Protein Signal Transduction Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Ral Protein Signal Transduction
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular volume ( 29403010 27863252)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		43 interacting genes: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP126 CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN H2AC20 H3C1 H4C1 HAP1 HOOK2 ING4 KATNBL1 KCTD13 LRIF1 MAP2K1 MCM2 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPTIN5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165	14 interacting genes: CCDC90B CRMP1 EEF1G HRAS KAT5 KAT7 KPNA2 KRAS NOTCH2NLA NRAS RAC1 RALA RAP1B UNC119
Entrez ID		11143	5863
HPRD ID		07135	03810
Ensembl ID		ENSG00000136504	ENSG00000237441
Uniprot IDs		O95251	A0A024RCS9 O15211
PDB IDs		5GK9
Enriched GO Terms of Interacting Partners?
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