PRDM4 and SERTAD1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		PRDM4	SERTAD1
Description		PR/SET domain 4	SERTA domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Histone Methyltransferase Complex	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Methyltransferase Activity Chromatin DNA Binding Sequence-specific DNA Binding Metal Ion Binding Histone Methyltransferase Binding	Protein Binding
	Biological Process	Transcription By RNA Polymerase II Histone H4-R3 Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Proliferation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		p75NTR negatively regulates cell cycle via SC1
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Sleep duration ( 30846698)	Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)
Interacting Genes		6 interacting genes: CTNNBL1 EIF4E EMX1 MSRB3 SERTAD1 SMAD3	39 interacting genes: ADCY1 ASB8 ATXN7L3 CCND2 CDK4 CDKN2A CHURC1 CIB3 COPB1 CREBBP DENND4A EGLN3 ELOC EP300 FAH HIVEP1 HSPB1 KAT2B KLHL42 MVP NEDD4 P4HA3 PATE1 POT1 PRDM4 RBX1 RCHY1 ROPN1 SETD7 SFI1 SMAD3 SPEN STAT5B SUPT7L TGM2 TLR4 TRIM28 XIAP ZNF410
Entrez ID		11108	29950
HPRD ID		10425	15326
Ensembl ID		ENSG00000110851	ENSG00000197019
Uniprot IDs		A0A024RBM7 B3KPI0 Q9UKN5	Q53GC0 Q9UHV2
PDB IDs		2L9Z 3DB5
Enriched GO Terms of Interacting Partners?
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