PRDM4 and EMX1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		PRDM4	EMX1
Description		PR/SET domain 4	empty spiracles homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Histone Methyltransferase Complex	Nuclear Chromatin Nucleus Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Methyltransferase Activity Chromatin DNA Binding Sequence-specific DNA Binding Metal Ion Binding Histone Methyltransferase Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Transcription By RNA Polymerase II Histone H4-R3 Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Brain Development Post-embryonic Development Cerebral Cortex Regionalization Cerebral Cortex Neuron Differentiation Neuron Differentiation Response To Drug Brain Morphogenesis Homeostasis Of Number Of Cells Radial Glial Cell Differentiation Neuroepithelial Cell Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation Neuron Projection Extension
Pathways		p75NTR negatively regulates cell cycle via SC1
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Sleep duration ( 30846698)	Schizophrenia ( 28991256 30285260)
Interacting Genes		6 interacting genes: CTNNBL1 EIF4E EMX1 MSRB3 SERTAD1 SMAD3	8 interacting genes: ALX4 ELK1 GTF2A1L HOXA10 LINC00839 POLR2D PRDM4 TP63
Entrez ID		11108	2016
HPRD ID		10425	08963
Ensembl ID		ENSG00000110851	ENSG00000135638
Uniprot IDs		A0A024RBM7 B3KPI0 Q9UKN5	Q04741
PDB IDs		2L9Z 3DB5
Enriched GO Terms of Interacting Partners?
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