SERTAD1 and DENND4A

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		SERTAD1	DENND4A
Description		SERTA domain containing 1	DENN domain containing 4A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytosol
	Molecular Function	Protein Binding	DNA Binding Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Proliferation Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription, DNA-templated
Pathways			RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)	Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Hemoglobin concentration ( 27863252) Intelligence (MTAG) ( 29326435) Logical memory (delayed recall) in normal cognition ( 29274321) Mean corpuscular hemoglobin ( 29403010 20139978 27863252) Mean corpuscular hemoglobin concentration ( 29403010 27863252) Mean corpuscular volume ( 29403010 27863252) Red blood cell count ( 27863252) Red blood cell traits ( 23222517)
Interacting Genes		39 interacting genes: ADCY1 ASB8 ATXN7L3 CCND2 CDK4 CDKN2A CHURC1 CIB3 COPB1 CREBBP DENND4A EGLN3 ELOC EP300 FAH HIVEP1 HSPB1 KAT2B KLHL42 MVP NEDD4 P4HA3 PATE1 POT1 PRDM4 RBX1 RCHY1 ROPN1 SETD7 SFI1 SMAD3 SPEN STAT5B SUPT7L TGM2 TLR4 TRIM28 XIAP ZNF410	6 interacting genes: CEBPE CLK1 PCBD1 SERTAD1 TLX3 YWHAG
Entrez ID		29950	10260
HPRD ID		15326	02662
Ensembl ID		ENSG00000197019	ENSG00000174485
Uniprot IDs		Q53GC0 Q9UHV2	Q05C90 Q7Z401
PDB IDs
Enriched GO Terms of Interacting Partners?
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