PIM2 and TRIM14

Number of citations of the paper that reports this interaction (PubMedID 29053956)
17

Data Source:
BioGRID (two hybrid)

		PIM2	TRIM14
Description		Pim-2 proto-oncogene, serine/threonine kinase	tripartite motif containing 14
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Mitochondrial Outer Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Molecular_function Zinc Ion Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Proliferation Apoptotic Mitochondrial Changes Response To Virus Positive Regulation Of Autophagy Positive Regulation Of Macroautophagy Negative Regulation Of Protein Binding Negative Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Protein Stabilization	Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS			Multiple sclerosis ( 31604244)
Interacting Genes		14 interacting genes: ATXN1 BAD CUTC DAPK1 FBH1 FBXO7 GSK3B HNRNPH3 IKBKG NDUFB8 RPL21 SOCS1 TRIM14 ZNF821	52 interacting genes: ABCF3 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H CENPC CSPP1 EIF3G ETFBKMT FAT1 HERC3 ITM2A IVNS1ABP KAT2B KIF3A LAMTOR1 MITD1 MNAT1 MRPL24 NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR2G PPP2R3C RAB5A RAB9A RBM33 RLF RNF125 RNF20 SMARCB1 SMIM3 STK38 TAX1BP1 TMEM167A UBE2B UBE2N UNK WDR35 WRNIP1 ZC4H2 ZFP36L2 ZNF652
Entrez ID		11040	9830
HPRD ID		02244	05948
Ensembl ID		ENSG00000102096	ENSG00000106785
Uniprot IDs		A0A024QYW7 Q9P1W9	A0A024R165 Q14142
PDB IDs		2IWI 4X7Q
Enriched GO Terms of Interacting Partners?
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