MORF4L1 and HMBOX1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MORF4L1	HMBOX1
Description		mortality factor 4 like 1	homeobox containing 1
Image
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Sin3 Complex Nuclear Speck NuA4 Histone Acetyltransferase Complex	Nuclear Chromosome, Telomeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body
	Molecular Function	Chromatin Binding Protein Binding Protein N-terminus Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Chromatin Silencing Cell Proliferation Histone Acetylation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Coronary artery disease ( 30104761) Coronary heart disease ( 21378988) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Pulse pressure ( 27841878 30578418) Squamous cell lung carcinoma ( 28604730)	Obesity-related traits ( 23251661)
Interacting Genes		42 interacting genes: APP ARRDC3 BEND7 CALM1 CAMK2B CEP57L1 EP300 FAM9B FHL3 FXR2 GMCL1 GOLGA2 H3-4 HINFP HMBOX1 IKZF1 L3MBTL3 LMNA LZTS2 MEOX1 MRFAP1 MRFAP1L1 MRGBP MSL1 NAB2 NAV2 NMI PBXIP1 PHF12 PSMC1 RACGAP1 RB1 REL SH3GLB2 TEX11 TFCP2 THAP1 TNIP1 TNNT1 TRIM41 ZBTB10 ZBTB9	49 interacting genes: ABITRAM AEBP2 APP ATP5PO BYSL C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM74A4 FARS2 FNDC11 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 WT1 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688
Entrez ID		10933	79618
HPRD ID		09532	07964
Ensembl ID		ENSG00000185787	ENSG00000147421
Uniprot IDs		Q9UBU8	D3DSU2 Q6NT76
PDB IDs		2AQL 2EFI 2F5J 2F5K 2LKM 2N1D 6AGO 6INE	2CUF 4J19
Enriched GO Terms of Interacting Partners?
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