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RACK1 and SREK1
Number of citations of the paper that reports this interaction (PubMedID
14559993
)
14
Data Source:
HPRD
(in vitro, two hybrid, in vivo)
RACK1
SREK1
Description
receptor for activated C kinase 1
splicing regulatory glutamic acid and lysine rich protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Phagocytic Cup
Cell
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Small Ribosomal Subunit
Cytosolic Small Ribosomal Subunit
Dendrite
Midbody
Neuronal Cell Body
Perikaryon
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
IRE1-RACK1-PP2A Complex
Nucleoplasm
Spliceosomal Complex
Nuclear Speck
Molecular Function
RNA Binding
Protein Kinase C Binding
Signaling Receptor Binding
Protein Binding
Ion Channel Inhibitor Activity
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Enzyme Binding
Protein Phosphatase Binding
Protein Tyrosine Kinase Inhibitor Activity
Cyclin Binding
Receptor Tyrosine Kinase Binding
Signaling Adaptor Activity
SH2 Domain Binding
Protein Homodimerization Activity
Ribosome Binding
Cadherin Binding
BH3 Domain Binding
Molecular Adaptor Activity
RNA Binding
Protein Binding
Biological Process
Positive Regulation Of Protein Phosphorylation
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cell Cycle
Gastrulation
Negative Regulation Of Gene Expression
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Viral Process
Protein Ubiquitination
Negative Regulation Of Translation
Negative Regulation Of Wnt Signaling Pathway
Negative Regulation Of Cell Growth
Positive Regulation Of Cell Migration
Positive Regulation Of Protein Complex Assembly
Negative Regulation Of Protein Binding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Localization
Negative Regulation Of Peptidyl-serine Phosphorylation
Positive Regulation Of Golgi To Plasma Membrane Protein Transport
Positive Regulation Of Apoptotic Process
Pigmentation
Positive Regulation Of GTPase Activity
Rhythmic Process
Negative Regulation Of Phagocytosis
Regulation Of Cell Division
Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Regulation Of Cell Cycle
Negative Regulation Of Protein Kinase B Signaling
Positive Regulation Of Mitochondrial Depolarization
Negative Regulation Of Protein Tyrosine Kinase Activity
Cellular Response To Glucose Stimulus
Cellular Response To Growth Factor Stimulus
Rescue Of Stalled Ribosome
Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Negative Regulation Of Hydrogen Peroxide-induced Neuron Death
Regulation Of Establishment Of Cell Polarity
Positive Regulation Of Ceramide Biosynthetic Process
Positive Regulation Of Gastrulation
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Pathways
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
TNFR1-mediated ceramide production
Drugs
Copper
Diseases
GWAS
Logical memory (delayed recall) in mild cognitive impairment (
29274321
)
Systolic blood pressure (
30224653
)
Interacting Genes
99 interacting genes:
ACTN2
ADH1B
ADRB2
AGTRAP
AR
ATG14
ATG5
AURKB
BCL2L11
BECN1
BRCA1
CCNA1
CDKN1A
CHERP
CSF2RB
DDX19B
DNM1
DYNLL1
EED
EIF6
ELOB
EP300
EPOR
ESR1
ESS2
FBXW7
FYN
GABRB3
GATA4
GNB1
GOLM1
GRAP2
GRIN2B
HABP4
HIF1A
HNRNPH2
IFNAR1
IFNAR2
IGF1R
IK
IL2RB
IL4R
IL7R
INSR
ITGB1
ITGB2
ITGB5
ITGB7
JAK1
LARP4B
LRP12
MAPK6
MCPH1
MKRN2
MTNR1A
NFATC1
NR3C1
NSMAF
OLA1
PABPC1
PDE4D
PIK3R4
PLCG1
PLEC
PRKAA1
PRKAB2
PRKCA
PRKCB
PRKCD
PRKCE
PRKD1
PRPF31
PTN
PTOV1
PTPRM
RASA1
RASA3
RB1
RHOA
SAT1
SLC27A6
SLC6A3
SRC
SREK1
ST7
STAT1
STAT3
SUMO4
SYT1
TARDBP
TBXA2R
TNFRSF1A
TP63
TP73
TSC22D4
TUBB
TUBG1
TYK2
WDR83
55 interacting genes:
CD8A
CSNK2A1
DDX17
DDX39B
DDX3X
DGKA
DGKD
EFTUD2
ELAVL1
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPC
HNRNPD
HNRNPH1
HNRNPK
HNRNPU
ILF2
MDM2
NCL
NPM1
PABPC1
PABPC4
PARP1
PIN1
RACK1
RBM10
RBMX
SAFB
SF3A3
SF3B3
SFPQ
SH3GLB2
SNRPD1
SNRPD3
SRPK1
SRPK2
SRPK3
SRSF1
SRSF10
SRSF11
SRSF2
SRSF3
SRSF4
SRSF5
SRSF6
SRSF7
SRSF8
SSRP1
SUPT16H
TARBP1
THRAP3
TRA2B
YBX1
ZRANB2
Entrez ID
10399
140890
HPRD ID
01503
18043
Ensembl ID
ENSG00000204628
ENSG00000153914
Uniprot IDs
E9KL35
P63244
Q8WXA9
PDB IDs
4AOW
4UG0
4V6X
5A2Q
5AJ0
5FLX
5LKS
5OA3
5T2C
5VYC
6EK0
6FEC
6G18
6G51
6G53
6G5H
6G5I
6IP5
6IP6
6IP8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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