SREK1 and HNRNPA2B1

Number of citations of the paper that reports this interaction (PubMedID 14559993)
14

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SREK1	HNRNPA2B1
Description		splicing regulatory glutamic acid and lysine rich protein 1	heterogeneous nuclear ribonucleoprotein A2/B1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Nuclear Speck	Chromosome, Telomeric Region Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Membrane Nuclear Matrix Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding MiRNA Binding Single-stranded Telomeric DNA Binding Pre-mRNA Intronic Binding G-rich Strand Telomeric DNA Binding N6-methyladenosine-containing RNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome MRNA Processing MRNA Export From Nucleus Viral Process RNA Metabolic Process Primary MiRNA Processing Interleukin-12-mediated Signaling Pathway G-quadruplex DNA Unwinding Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Transport Regulation Of RNA Metabolic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Telomerase RNA Reverse Transcriptase Activity MiRNA Transport
Pathways			mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			Copper Artenimol
Diseases
GWAS		Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		55 interacting genes: CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 RACK1 RBM10 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B YBX1 ZRANB2	19 interacting genes: CDKN2A CSNK2A1 CSNK2B ERG ESR1 H3-4 HIPK3 HNRNPL HSPB1 LIG4 MAP4K2 MCPH1 NR4A1 SNRNP70 SREK1 TTF2 VHL YAE1 ZMYM2
Entrez ID		140890	3181
HPRD ID		18043	02526
Ensembl ID		ENSG00000153914	ENSG00000122566
Uniprot IDs		Q8WXA9	P22626
PDB IDs			1X4B 5EN1 5HO4 5WWE 5WWF 5WWG
Enriched GO Terms of Interacting Partners?
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