SREK1 and EFTUD2

Number of citations of the paper that reports this interaction (PubMedID 14559993)
14

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		SREK1	EFTUD2
Description		splicing regulatory glutamic acid and lysine rich protein 1	elongation factor Tu GTP binding domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Nuclear Speck	Nucleus Nucleoplasm Cytosol Cajal Body Membrane Nuclear Speck Intracellular Membrane-bounded Organelle U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding GTPase Activity Protein Binding GTP Binding U5 SnRNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome Cellular Response To Drug Response To Cocaine
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)	Asthma ( 31619474) Craniofacial microsomia ( 26853712)
Interacting Genes		55 interacting genes: CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 RACK1 RBM10 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B YBX1 ZRANB2	12 interacting genes: ARPC3 CYFIP1 GOLM1 GSK3B HINFP LSM8 PIN1 SF3B3 SF3B4 SNRNP200 SREK1 WBP4
Entrez ID		140890	9343
HPRD ID		18043	04869
Ensembl ID		ENSG00000153914	ENSG00000108883
Uniprot IDs		Q8WXA9	B3KX19 Q15029
PDB IDs			3JCR 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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