SREK1 and DDX39B

Number of citations of the paper that reports this interaction (PubMedID 14559993)
14

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		SREK1	DDX39B
Description		splicing regulatory glutamic acid and lysine rich protein 1	DExD-box helicase 39B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Nuclear Speck	Transcription Export Complex Nucleus Nucleoplasm Spliceosomal Complex U4 SnRNP U6 SnRNP Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity ATPase Activity U6 SnRNA Binding U4 SnRNA Binding Identical Protein Binding ATP-dependent Protein Binding Protein-containing Complex Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Liver Development RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing RNA Secondary Structure Unwinding MRNA 3'-end Processing Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Translation Viral MRNA Export From Host Cell Nucleus Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Vascular Smooth Muscle Cell Proliferation Negative Regulation Of DNA Damage Checkpoint Positive Regulation Of DNA Biosynthetic Process
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Isopropyl Alcohol
Diseases
GWAS		Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) Mean platelet volume ( 27863252) Monocyte percentage of white cells ( 27863252) Mosquito bite size ( 28199695) Myositis ( 26291516) Ulcerative colitis ( 28067908)
Interacting Genes		55 interacting genes: CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 RACK1 RBM10 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B YBX1 ZRANB2	24 interacting genes: ALYREF BARD1 DDX39A DNM2 EXOSC9 FANCA HIPK2 HNRNPLL IL7R LUZP4 NCBP2 PIAS2 RBM39 RPS15A SARNP SREK1 SRPK2 STRN4 TDG THOC3 THOC6 TUBB3 YWHAG ZHX1
Entrez ID		140890	7919
HPRD ID		18043	00805
Ensembl ID		ENSG00000153914	ENSG00000198563
Uniprot IDs		Q8WXA9	A0A024RCM3 Q13838
PDB IDs			1T5I 1T6N 1XTI 1XTJ 1XTK
Enriched GO Terms of Interacting Partners?
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