SLC12A6 and OXSR1

Data Source:
HPRD (two hybrid)

		SLC12A6	OXSR1
Description		solute carrier family 12 member 6	oxidative stress responsive kinase 1
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Synapse	Cytosol Extracellular Exosome
	Molecular Function	Ammonium Transmembrane Transporter Activity Potassium:chloride Symporter Activity	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Identical Protein Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Angiogenesis Ion Transport Cell Volume Homeostasis Chemical Synaptic Transmission Chloride Ion Homeostasis Potassium Ion Homeostasis Cellular Hypotonic Salinity Response Ammonium Import Across Plasma Membrane Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Protein Phosphorylation Response To Oxidative Stress Signal Transduction Osmosensory Signaling Pathway Positive Regulation Of T Cell Chemotaxis Peptidyl-threonine Phosphorylation Intracellular Signal Transduction Chemokine (C-C Motif) Ligand 21 Signaling Pathway Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway Protein Autophosphorylation Cellular Hypotonic Response Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Cellular Response To Chemokine
Pathways		Cation-coupled Chloride cotransporters Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)
Drugs		Potassium chloride	Fostamatinib
Diseases		Agenesis of the corpus callosum with peripheral neuropathy (ACCPN)
GWAS		Barrett's esophagus x pack-years of smoking exposure interaction ( 29551738)	Gut microbiota (bacterial taxa) ( 27723756) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		3 interacting genes: DYSF OXSR1 STK39	10 interacting genes: APP BMPR1B PAK1 RELL1 RELL2 SLC12A1 SLC12A2 SLC12A6 SMURF1 TGFBR1
Entrez ID		9990	9943
HPRD ID		09220	06809
Ensembl ID		ENSG00000140199	ENSG00000172939
Uniprot IDs		A0A024R9I5 A0A024R9K8 Q6NSI7 Q9UHW9	O95747
PDB IDs		6M1Y 6M22 6Y5R 6Y5V	2V3S 2VWI 3DAK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?