OXSR1 and RELL2

Data Source:
BioGRID (two hybrid)

		OXSR1	RELL2
Description		oxidative stress responsive kinase 1	RELT like 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Basement Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Identical Protein Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding Collagen Binding
	Biological Process	Protein Phosphorylation Response To Oxidative Stress Signal Transduction Osmosensory Signaling Pathway Positive Regulation Of T Cell Chemotaxis Peptidyl-threonine Phosphorylation Intracellular Signal Transduction Chemokine (C-C Motif) Ligand 21 Signaling Pathway Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway Protein Autophosphorylation Cellular Hypotonic Response Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Cellular Response To Chemokine	Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of P38MAPK Cascade
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494)	Refractive error ( 32231278)
Interacting Genes		10 interacting genes: APP BMPR1B PAK1 RELL1 RELL2 SLC12A1 SLC12A2 SLC12A6 SMURF1 TGFBR1	21 interacting genes: ANKRD46 ASPH CDIPT CLDND2 COL4A5 FAM3C LPAR3 MIP NSG1 OXSR1 PLP1 RELL1 RTP2 SEC22B SLC30A8 SLC35A1 SMIM1 TFRC TSPAN33 TSPO2 ZFPL1
Entrez ID		9943	285613
HPRD ID		06809	12830
Ensembl ID		ENSG00000172939	ENSG00000164620
Uniprot IDs		O95747	Q8NC24
PDB IDs		2V3S 2VWI 3DAK
Enriched GO Terms of Interacting Partners?
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