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CDC34 and MARCHF2
Data Source:
BioGRID
(pull down)
CDC34
MARCHF2
Description
cell division cycle 34, ubiqiutin conjugating enzyme
membrane associated ring-CH-type finger 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Nuclear Speck
Lysosomal Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Endosome Membrane
Integral Component Of Membrane
Cytoplasmic Vesicle
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Conjugating Enzyme Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Protein Polyubiquitination
DNA Replication Initiation
Cellular Protein Modification Process
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Cellular Response To Interferon-beta
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Neuron Apoptotic Process
Negative Regulation Of CAMP-mediated Signaling
Response To Growth Factor
Protein K48-linked Ubiquitination
Positive Regulation Of Inclusion Body Assembly
Endocytosis
Protein Ubiquitination
Pathways
Downstream TCR signaling
FCERI mediated NF-kB activation
CLEC7A (Dectin-1) signaling
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes
56 interacting genes:
ATF5
BTRC
CCNB1
CDK9
CDKN1B
CREM
CSNK2B
CTNNB1
CUL1
CUL2
CUL3
EGFR
FBXL2
FBXL3
FBXO32
FBXO4
FBXO7
FBXW2
FBXW7
HIF1A
ING4
ITCH
MARCHF1
MARCHF2
MDM2
MEOX1
MEOX2
MUL1
MYBL2
MYOD1
NEDD4L
NEDD8
NFKBIA
PPARA
PPARG
PRKN
PTTG1
RBX1
RELA
RNF31
RNF7
ROCK1
SDCBP
SIAH1
SKP2
TBL1X
TP53
TRIM21
TRIM28
TRIM29
UBA1
UBB
VHL
WWP2
ZFAND6
ZNRF1
30 interacting genes:
AQP6
CCL4
CD79A
CDC34
CFTR
CREB3L1
ERGIC3
F11R
FAM209A
FATE1
GJA8
GPX8
KASH5
LDLRAD1
LGR4
MUC1
PEX12
PLPPR2
SCN3B
SSMEM1
STX6
SYNE4
TMEM106C
TMEM179B
TMEM52B
TMEM86B
TSPAN12
TSPO2
UBE2D1
UBE2H
Entrez ID
997
51257
HPRD ID
00306
14361
Ensembl ID
ENSG00000099804
ENSG00000099785
Uniprot IDs
A0A024R1Z1
P49427
Q9P0N8
PDB IDs
2OB4
3RZ3
4MDK
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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