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MVP and ADAMTSL4
Data Source:
BioGRID
(two hybrid)
MVP
ADAMTSL4
Description
major vault protein
ADAMTS like 4
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Nucleus
Nuclear Pore
Cytoplasm
Cytosol
Cytoskeleton
Membrane
Secretory Granule Lumen
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Ficolin-1-rich Granule Lumen
Interstitial Matrix
Endoplasmic Reticulum Lumen
Extracellular Matrix
Collagen-containing Extracellular Matrix
Molecular Function
Protein Binding
Protein Kinase Binding
Protein Phosphatase Binding
Identical Protein Binding
Protease Binding
Metalloendopeptidase Activity
Protein Binding
Biological Process
Protein Transport
Negative Regulation Of Protein Autophosphorylation
ERBB Signaling Pathway
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Neutrophil Degranulation
MRNA Transport
Negative Regulation Of Protein Tyrosine Kinase Activity
Epithelial Cell Development
Proteolysis
Apoptotic Process
Extracellular Matrix Organization
Positive Regulation Of Apoptotic Process
Pathways
Neutrophil degranulation
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
Ectopia lentis
GWAS
Asthma (
32296059
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Coronary artery disease (
29212778
)
Cortical surface area (min-P) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (min-P) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Migraine (
27322543
)
Refractive error (
32231278
)
Rhegmatogenous retinal detachment (
23585552
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
64 interacting genes:
ADAMTSL4
BANP
C1orf94
CALCOCO2
CAMK2B
CKAP4
DISC1
DLX2
DTX2
EPHX2
ESR1
FNDC3B
GIT2
GOLGA2
HP
IHO1
KCTD9
KPNA2
KPNA3
MDFI
MEOX1
MEOX2
MID2
MRTFA
MT-CYB
NNT
NOTCH2NLA
NRF1
NTAQ1
PARP4
PIH1D2
PLSCR1
POT1
PSTPIP1
PTEN
PTPN11
RAB3IP
RBPMS
REL
RHOXF2
RIMBP3
RNF111
SAXO1
SERTAD1
SKIL
SLC2A4
STN1
TCF4
TENT5C
TFCP2
TLE5
TOLLIP
TP53
TRAF2
TRIM27
TRIM42
TRIP13
TRIP6
TSPOAP1
UBC
UBTD2
VAC14
ZBTB32
ZMIZ2
209 interacting genes:
ADAM12
ADAMTSL5
ALPP
AMMECR1
APOL6
AQP1
ARNT2
ASPSCR1
ATG9A
BAG4
BANF2
BOLA2
BOLA2B
BRME1
CATSPER1
CBX3
CCDC26
CFAP206
CHCHD2
CHERP
CHIC2
CHRD
CHRNG
CLEC18A
COL8A1
CPNE7
CREB5
CST2
CTSB
CXCL16
CYP2S1
CYSRT1
DGCR6
DGCR6L
DIP2A
DLK2
DNPEP
DSCR8
EFEMP2
EIF4E2
EPDR1
ERCC3
EXOSC5
FAH
FAM124B
FARS2
FBLN1
FBXO17
FBXW5
FHL3
FKBP1B
FLNA
FRS3
GATA2
GIP
GLRX3
GLYCTK
GMCL2
GNE
GNG13
GNMT
GOLGA8EP
GSTP1
GUCD1
HEXIM2
HGF
HNRNPLL
HOXA1
HOXC8
HSD3B7
INS
IP6K1
ITGB2
ITGB4
JOSD1
KCTD7
KCTD9
KIF1A
KLHL38
KRTAP1-1
KRTAP1-5
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-3
KRTAP19-2
KRTAP21-2
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-7
KRTAP5-9
KRTAP6-2
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-4
LCE1A
LCE1B
LCE1C
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LCE3E
LCE4A
LGALS14
LHX4
LINC00671
LMO1
LMO2
LMO4
LNX1
LONRF1
LRFN4
LRRC29
MAGOHB
MAPKBP1
MGAT5B
MID2
MKRN3
MORN3
MVP
MYLIP
MYO15B
NATD1
NBPF19
NEK8
NFKBID
NMUR2
NOTCH2NLA
NR4A3
NTAQ1
NTF4
NTN4
NUFIP2
OLFM3
OTX1
PCSK5
PID1
PIN1
PKN1
PLSCR1
PLSCR4
POLD1
POLR1C
POU4F2
PRKAB2
PRR19
PTGER3
PTPMT1
QPRT
R3HDM2
RAB2B
RCHY1
RGL2
RHOJ
RPS19BP1
RUNX1T1
SALL2
SCNM1
SHFL
SLC13A5
SLC23A1
SLC6A20
SLIT1
SMARCC1
SORBS3
SPATA8
SPINK2
SPRY1
SPRY2
STK16
SUSD6
TAPBPL
TCEA2
TFAP2D
TGFB1
THAP6
TMEM150A
TMSB4XP6
TOP3B
TRIM42
TRIM55
TRIM63
TRIP6
TSSK3
TUBGCP4
USP21
VASN
VENTX
VWC2
ZFHX2
ZNF330
ZNF414
ZNF417
ZNF587
Entrez ID
9961
54507
HPRD ID
05475
18237
Ensembl ID
ENSG00000013364
ENSG00000143382
Uniprot IDs
Q14764
X5D2M8
X5D7K9
X5DNU0
A0A669KBE7
B7ZMJ3
Q6UY14
Q9UFG7
PDB IDs
1Y7X
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Intersection)
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